The inherited diseases of hemoglobin are an emerging global health burden
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Cites background from "The inherited diseases of hemoglobi..."
...prevalence and burden of these disorders are still lacking [6,21,37]....
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...Conclusion Multiple warnings regarding the effect of epidemiological and demographic transitions in low-income countries and their consequences for SCA burden have been published [6,66]....
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...Five disorders constitute approximately 25% of these births, two of which, haemoglobinopathy and glucose-6-phosphate dehydrogenase deficiency, are monogenic diseases [6]....
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...It has been suggested that the burden of haemoglobinopathies is going to increase over the coming decades [6,39]....
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...In the long term, in the absence of a definitive treatment for SCA, the best intervention to reduce excess mortality caused by this disorder and to keep public health costs associated with the follow-up care of SCA patients through their lifetime manageable, especially in lowincome countries, is to avoid the births of affected newborns [6,37]....
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References
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