Open AccessJournal Article
The Laboratory Rat: Relating Its Age With Human's
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TLDR
The overall findings indicate that rats grow rapidly during their childhood and become sexually mature at about the sixth week, but attain social maturity 5-6 months later, which must be taken into consideration while analyzing the results or selecting the dose of any research in rats when age is a crucial factor.Abstract:
By late 18th or early 19th century, albino rats became the most commonly used experimental animals in numerous biomedical researches, as they have been recognized as the preeminent model mammalian system. But, the precise correlation between age of laboratory rats and human is still a subject of debate. A number of studies have tried to detect these correlations in various ways, But, have not successfully provided any proper association. Thus, the current review attempts to compare rat and human age at different phases of their life. The overall findings indicate that rats grow rapidly during their childhood and become sexually mature at about the sixth week, but attain social maturity 5-6 months later. In adulthood, every day of the animal is approximately equivalent to 34.8 human days (i.e., one rat month is comparable to three human years). Numerous researchers performed experimental investigations in albino rats and estimated, in general, while considering their entire life span, that a human month resembles every-day life of a laboratory rat. These differences signify the variations in their anatomy, physiology and developmental processes, which must be taken into consideration while analyzing the results or selecting the dose of any research in rats when age is a crucial factor.read more
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Men and mice: Relating their ages.
Sulagna Dutta,Pallav Sengupta +1 more
TL;DR: This review article is the first to establish a precise relation between mice age and human age, following the previous article, which explained the relation in ages of laboratory rats with humans in detail.
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Toward a neurology of loneliness.
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Samuel J. Jackson,Nick Andrews,Doug Ball,Ilaria Bellantuono,James Gray,Lamia Hachoumi,Alan Holmes,Judy Latcham,Anja Petrie,Paul Potter,Andrew S.C. Rice,A.A. Ritchie,Michelle Stewart,Carol Strepka,Mark Yeoman,Kathryn Chapman +15 more
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Repeated mild traumatic brain injury: potential mechanisms of damage.
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References
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TL;DR: Developmental changes in prefrontal cortex and limbic brain regions of adolescents across a variety of species, alterations that include an apparent shift in the balance between mesocortical and mesolimbic dopamine systems likely contribute to the unique characteristics of adolescence.
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The laboratory rat
TL;DR: Anesthesia and Surgery Assisted Reproduction Bacterial and Mycotic Disease Behavior and Behavioral Analysis Cardiovascular Research Embryology and Teratology Euthanasia and Necropsy Experimental Modeling and Research Methodology Gerontology and Age-Associated Lesions Health Surveillance Hematology and Clinical Biochemistry Historical Foundations.
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Grant's Atlas of Anatomy
TL;DR: Renowned for its accuracy, pedagogy, and clinical relevance, this classic atlas boasts significant enhancements, including updated artwork, new conceptual diagrams, and vibrantly re-colored illustrations.
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Health Impacts of Yoga and Pranayama: A State-of-the-Art Review
TL;DR: Yoga is reported to reduce stress and anxiety, improves autonomic functions by triggering neurohormonal mechanisms by the suppression of sympathetic activity, and even, now-a-days, several reports suggested yoga is beneficial for physical health of cancer patients.