Journal ArticleDOI
The Lesch-Nyhan syndrome.
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TLDR
The authors suggest that these children with the Lesch-Nyhan syndrome may have a very low threshold for the activation of a mechanism that controls repetitive, compulsive, pain-causing behavior.Abstract:
The authors report their observations of five children with the Lesch-Nyhan syndrome and review the literature to describe the general characteristics of the disorder, the development and types of self-mutilative behavior, and the types of outward-directed aggression. The authors suggest that these children may have a very low threshold for the activation of a mechanism that controls repetitive, compulsive, pain-causing behavior. This factor may also explain other forms of self-destructive behavior in children and may represent the psychobiological basis for the development of masochistic behavior.read more
Citations
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The motivation of self-injurious behavior: A review of some hypotheses.
TL;DR: Five major hypotheses concerning the motivation of self-injurious behavior are suggested; each is an attempt to establish ego boundaries or to reduce guilt and data bearing on each hypothesis are reviewed and evaluated.
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Human Bone Marrow Mesenchymal Stem Cell Behaviors on PCL/Gelatin Nanofibrous Scaffolds Modified with A Collagen IV-Derived RGD-Containing Peptide
Ali Mota,Abbas Sahebghadam Lotfi,Jalal Barzin,Mostafa Hatam,Behzad Adibi,Zahra Khalaj,Mohammad Massumi +6 more
TL;DR: This peptide modified nanofibrous scaffold can be a promising biomaterial for tissue engineering and regenerative medicine with the use of hBMSCs.
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Parasexual Approaches to the Genetics of Man
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TL;DR: Three methods are used for cell hybridization and chromosome elimination in somatic cells and it is important to adjust the density and/or ratio of one parental cell type to the other to maximize yield of heterokaryons.
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Compulsive, self-injurious, and autistic behavior in children and adolescents with fragile X syndrome.
TL;DR: The data suggest that autistic and compulsive behaviors are highly prevalent in fragile X syndrome and that lowered levels of FMRP and cortisol may be biological markers for these behaviors.
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