The malnutrition of obesity: micronutrient deficiencies that promote diabetes.
Citations
544 citations
Cites background from "The malnutrition of obesity: micron..."
...Frank deficiency in biotin is rarely reported, although lower circulating levels of biotin have been reported in those suffering gluco-regulatory dysfunction, for instance Type II diabetes, alongside an inverse relationship between fasting plasma glucose and biotin levels [18]....
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...In a similar vein, both Type II diabetes and increased fasting plasma glucose levels have been found to be associated with lower levels of biotin [18]....
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...B7 Biotin Eggs, liver, pork, leafy vegetables 30 (μg) - biotin (carboxylation reactions) Seborrheic eczematous rash, tingling/burning of the extremities [17] Depression, lethargy, hallucinations, seizures [17] Type II diabetes, poor gluco-regulation [18]...
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...Similarly, thiamine deficiency rates have been reported to vary between 17% and 79% in patients suffering from the gluco-regulatory disease diabetes [9,18]....
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...Biotin plays a key role in glucose metabolism and haemostasis, including regulation of hepatic glucose uptake, gluconeogenesis (and lipogenesis), insulin receptor transcription and pancreatic β-cell function [18]....
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371 citations
Cites background from "The malnutrition of obesity: micron..."
...High rate of vitamin C deficiency has been found in obese individuals and diabetic subjects [76,80]....
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...Deficiencies in minerals and vitamins can also contribute to impaired antioxidant defenses [30,76]; poor selenium and zinc nutritional state has been reported in obese children and adolescents, especially in children with central adiposity [77,78], whereas morbidly obese patients show magnesium, selenium, iron, and zinc deficiencies [79]....
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234 citations
155 citations
Cites background from "The malnutrition of obesity: micron..."
...Malnutrition should be considered in obese patients who are a growing demographic in developed countries and with a proportional increase in TJA [15,17,31,32]....
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143 citations
References
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"The malnutrition of obesity: micron..." refers background in this paper
...While some controversy exists over treatment targets in individuals with mild insufficiency of vitamin D especially for the purported extraskeletal effects of vitamin D supplementation, [10, 11] a significant amount of evidence suggests there may be some beneficial effect in using vitamin D supplementation for improvement in glucose metabolism and insulin signaling in patients with type 2 diabetes or impaired glucose tolerance [12]....
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6,998 citations
3,817 citations
"The malnutrition of obesity: micron..." refers background in this paper
...The increased availability of low-cost, highcalorie, nutrient-poor foods over the past four decades is a key component to the rise in obesity worldwide [3]....
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...Multiple genetic, environmental and behavioral factors contribute to the increasing trend in obesity [1, 3]....
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2,947 citations