The NCI60 human tumour cell line anticancer drug screen
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...NCI60 cell line testing and some in vivo toxicity testing were carried out through NCI/DTP....
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...For the competitor-treated samples, 20 flasks of cells were treatedwith 0.5 mM (1S, 3R)-RSL3 (‘‘competitor’’) for 20min (F) Sensitivity profile of 53 cancer cell lines in the ‘‘NCI60’’ cell panel against eras (G) The eight RCC cell lines were retested with erastin to confirm their sensitivity (H) Erastin and RSL3 generated lipid ROS in the two RCC cell lines....
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...The potency of erastin was also determined in a 60-cancer cell line panel (NCI60) (Shoemaker, 2006) from eight diverse tissues, which revealed increased sensitivity of renal cell carcinomas (RCCs), compared to the other tissues examined (Figures 7F and S7D)....
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...For analysis of ZEB1 and miRNA expression in the NCI60 pane...
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...seems to have several advantages over the well-studied NCI60 panel of cancer cell lines, which contains only 7 breast cancer cell lines, most of which are the basal subtyp...
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References
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"The NCI60 human tumour cell line an..." refers methods in this paper
...A simple colorimetric (MTT) assay for use in immunology was introduced in 1983 (Ref...
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"The NCI60 human tumour cell line an..." refers methods in this paper
...This technology, which relies on the metabolic reduction of a tetrazolium dye in viable cells to a coloured formazan product, was adapted and evaluated for growth-inhibition screenin...
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