The potential role of hypocortisolism in the pathophysiology of stress-related bodily disorders.
Citations
3,278 citations
2,535 citations
Cites background from "The potential role of hypocortisoli..."
..., a phenomenon that is also observed in certain associated conditions such as fibromyalgia, chronic fatigue syndrome and post-traumatic stress disorde...
[...]
2,196 citations
1,725 citations
1,440 citations
Cites background from "The potential role of hypocortisoli..."
...Specifically, the combination of increased stress responsiveness with insufficient glucocorticoid signaling due to glucocorticoid receptor deficiency might have adverse effects in target systems that are regulated by glucocorticoids (Heim et al., 2000a; Raison and Miller, 2003)....
[...]
...The objective of our first study was to determine whether early-life stress in humans is associated with persistent sensitization of the HPA axis and the autonomic nervous system to mild stress in adulthood, thereby contributing to vulnerability to depression (Heim et al., 2000b; Figure 1)....
[...]
References
8,476 citations
5,932 citations
"The potential role of hypocortisoli..." refers background in this paper
...Based on experimental data and theoretical considerations, several authors have posited theories on the development and the physiological meaning of hypocortisolism (Dienstbier, 1989; Hellhammer and Wade, 1993; Henry, 1993; Yehuda et al., 1993b; McEwen, 1998)....
[...]
3,667 citations
3,599 citations
3,050 citations
"The potential role of hypocortisoli..." refers result in this paper
...Similar to these findings, Natelson et al. (1988) observed a gradual decrease in basal corticosterone levels in rats, which were weekly exposed to the same stressor....
[...]