Journal ArticleDOI
The relationship between vitamin D and parathyroid hormone: calcium homeostasis, bone turnover, and bone mineral density in postmenopausal women with established osteoporosis.
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TLDR
This study identifies a distinct group of patients with hypovitaminosis D and a blunted PTH response who show a disruption in calcium homeostasis but protected against PTH-mediated bone loss and has clinical implications with respect to disease definition.About:
This article is published in Bone.The article was published on 2004-07-01. It has received 243 citations till now. The article focuses on the topics: Bone density & Vitamin D and neurology.read more
Citations
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Journal ArticleDOI
Prevalence of Vitamin D Inadequacy among Postmenopausal North American Women Receiving Osteoporosis Therapy
Michael F. Holick,Ethel S. Siris,Neil Binkley,Mary K. Beard,Aliya Khan,Jennifer T. Katzer,Richard A. Petruschke,Erluo Chen,Anne E. de Papp +8 more
TL;DR: Prevalence of suboptimal 25(OH)D was significantly higher in subjects who took less than 400 vs. 400 IU/d or more vitamin D, and there was a significant negative correlation between serum PTH concentrations and 25( OH)D.
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Effectiveness and safety of vitamin D in relation to bone health.
Ann Cranney,Tanya Horsley,Siobhan O'Donnell,Hope A. Weiler,Lorri Puil,Daylily S. Ooi,Stephanie A. Atkinson,Leanne M Ward,David Moher,David A. Hanley,Manchung Fang,Fatemeh Yazdi,Chantelle Garritty,Margaret Sampson,Nick Barrowman,Alex Tsertsvadze,Vasil Mamaladze +16 more
TL;DR: The largest body of evidence on vitamin D status and bone health was in older adults with a lack of studies in premenopausal women and infants, children and adolescents, and there was fair evidence of an association between low circulating 25(OH)D concentrations and established rickets.
Journal ArticleDOI
Bone mineralization defects and vitamin D deficiency: Histomorphometric analysis of iliac crest bone biopsies and circulating 25-hydroxyvitamin D in 675 patients
Matthias Priemel,Christoph von Domarus,Till Orla Klatte,Steffen Kessler,Julia Schlie,Simon Meier,Nils Proksch,Frederic Pastor,Clemens Netter,Thomas Streichert,Klaus Püschel,Michael Amling +11 more
TL;DR: The data demonstrate that pathologic mineralization defects of bone occur in patients with a serum 25(OH)D below 75 nmol/L and strongly argue that in conjunction with a sufficient calcium intake, the dose of vitamin D supplementation should ensure that circulating levels of 25( OH)D reach this minimum threshold to maintain skeletal health.
Journal ArticleDOI
The Vitamin D requirement in health and disease
TL;DR: The tolerable upper intake level (TUIL) is too low to permit optimization of Vitamin D status in the general population and actual toxicity is not seen below serum 25OHD values of 250nmol/L.
Journal ArticleDOI
Prevalence of vitamin D inadequacy among postmenopausal north american women receiving osteoporosis therapy
Michael F. Holick,Ethel S. Siris,Neil Binkley,Mary K. Beard,Aliya Khan,Jennifer T. Katzer,Richard A. Petruschke,Erluo Chen,Anne E. de Papp +8 more
TL;DR: More than half of North American women receiving therapy to treat or prevent osteoporosis have vitamin D inadequacy, underscoring the need for improved physician and public education regarding optimization of vitamin D status in this population.
References
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Journal ArticleDOI
Prediction of Creatinine Clearance from Serum Creatinine
Donald W. Cockcroft,M H Gault +1 more
TL;DR: A formula has been developed to predict Creatinine clearance from serum creatinine (Scr) in adult males: Ccr = (140 – age) (wt kg)/72 × Scr (mg/100ml) (15% less i).
Book
Vitamin D
TL;DR: In what case do you like reading so much? What about the type of the vitamin d the calcium homeostatic steroid hormone book? The needs to read? Well, everybody has their own reason why should read some books as discussed by the authors.
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Prevalence of Vitamin D Insufficiency in an Adult Normal Population
Marie-Claire Chapuy,Paul Preziosi,M. Maamer,S. Arnaud,Pilar Galan,Serge Hercberg,P. J. Meunier +6 more
TL;DR: The results showed that in French normal adults living in an urban environment with a lack of direct exposure to sunshine, diet failed to provide an adequate amount of vitamin D, and the clinical utility of winter supplementation with low doses ofitamin D was discussed.
Journal ArticleDOI
Redefining vitamin D insufficiency
Journal ArticleDOI
Occult vitamin D deficiency in postmenopausal US women with acute hip fracture
Meryl S. LeBoff,Lynn A. Kohlmeier,Shelley Hurwitz,Jennifer Franklin,John Wright,Julie Glowacki +5 more
TL;DR: Postmenopausal community-living women who presented with hip fracture showed occult vitamin D deficiency and suppression of parathyroid hormone at the time of fracture may reduce future fracture risk and facilitate hip fracture repair.