Journal ArticleDOI
The Response of Denervated Skeletal Muscle to Succinylcholine
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TLDR
The responses of denervated and normal canine gastroenemius muscle to succinylcholine (SCh) were compared and contrasted in regard to potassium (K+) flux &OV0312;O2, muscle tension, and electrical activity.Abstract:
The responses of denervated and normal canine gastroenemius muscle to succinylcholine (SCh) were compared and contrasted in regard to potassium (K+) flux O2, muscle tension, and electrical activity. K+ efflux and O2 of denervated muscle increased 20-fold and fourfold after SCh, respectively, while Kread more
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Succinylcholine-induced hyperkalemia in acquired pathologic states: etiologic factors and molecular mechanisms.
TL;DR: The nicotinic (neuronal) α7 acetylcholine receptors, recently described to be expressed in muscle also, can be depolarized not only by acetyl choline and succinylcholine but also by choline, persistently, and possibly play a critical role in the hyperkalemic response to succinyl choline in patients with up-regulated AChRs.
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Anaesthesia for Charcot-Marie-Tooth disease: a review of 86 cases
TL;DR: This survey supports the safe use of succinylcholine and MH triggering agents in Charcot-Marie-Tooth disease, a condition characterized by chronic muscular denervation, without untoward effects.
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Suxamethonium and Hyperkalaemia
TL;DR: The normal hyperkalaemic response to suxamethonium, the factors affecting it, the conditions in which it may be exaggerated, and the periods of high risk are described.
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Desaturation following rapid sequence induction using succinylcholine vs. rocuronium in overweight patients
TL;DR: The purpose of this study was to investigate the possible difference in desaturation during rapid sequence induction in overweight patients using either succinylcholine or rocuronium.
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Serum Cholinesterase Activity in Burned Patients. II: Anaesthesia, Suxamethonium and Hyperkalaemia
TL;DR: The importance of serum cholinesterase activity in burned patients was evaluated in relation to anaesthesia and a repeated administration of suxamethonium was included.