The RNA Polymerase II Core Promoter – the Gateway to Transcription
Citations
2,710 citations
Cites background from "The RNA Polymerase II Core Promoter..."
...Transcription factor binding at CGIs CGIs share little long-range sequence conservation, apart from an elevated CpG density and G+C content, and often lack core promoter elements such as the TATA box (Carninci et al. 2006; Juven-Gershon et al. 2008)....
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...…GENES & DEVELOPMENT TATA boxes, along with other core promoter elements (such as the BRE, DPE, and DCE), tend to be associated with focused transcriptional initiation, whereas CGIs tend to lack these elements and display dispersed initiation patterns (for review, see Juven-Gershon et al. 2008)....
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1,026 citations
Cites background from "The RNA Polymerase II Core Promoter..."
...The conventional view is that most genes contain a predominant TSS, the location of which is defined by core promoter elements...
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671 citations
635 citations
Cites background from "The RNA Polymerase II Core Promoter..."
...An interesting analogy is with TATA-less promoters, which use the same set of core transcription factors but involving different interactions with promoter sequences (Juven-Gershon et al., 2008; Sikorski and Buratowski, 2009)....
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575 citations
Cites background from "The RNA Polymerase II Core Promoter..."
...In various combinations, the elements of the core promoter sequence target the assembly of distinct preinitiation complexes (PICs) composed of the general transcription factors (GTFs...
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References
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