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The role of miRNAs in alveolar epithelial cells in emphysema.

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TLDR
In this article, the authors summarize recent findings on miRNAs' role in alveolar epithelial cells in emphysema, and they also serve as biomarkers of lung diseases and potential therapeutics.
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This article is published in Biomedicine & Pharmacotherapy.The article was published on 2021-11-01 and is currently open access. It has received 4 citations till now. The article focuses on the topics: Lung & COPD.

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Immunomodulatory Properties of Human Breast Milk: MicroRNA Contents and Potential Epigenetic Effects

TL;DR: This comprehensive work presents an up-to-date overview of the immunomodulatory constituents of HBM, highlighting its content of circulating microRNAs and the epigenetic effects of H BM, especially those regulated by miRNAs.
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The regulation of circRNA_kif26b on alveolar epithelial cell senescence via miR-346-3p is involved in microplastics-induced lung injuries.

TL;DR: In this paper , polystyrene microplastics (PS-MPs) were used for a 35-day inhalation exposure in SPF-grade Sprague-Dawley (SD) rats.
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Qilongtian ameliorate bleomycin-induced pulmonary fibrosis in mice via inhibiting IL-17 signal pathway

TL;DR: In this article , the effect of Qilongtian (QLT) in treating Bleomycin (BLM) induced pulmonary fibrosis (PF) mice was investigated, and it was shown that QLT significantly reduced the inflammatory injury, hydroxy-proline content, and collagen deposition of pulmonary tissue in BLM-induced PF mice.
References
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Journal ArticleDOI

MicroRNAs: Target Recognition and Regulatory Functions

TL;DR: The current understanding of miRNA target recognition in animals is outlined and the widespread impact of miRNAs on both the expression and evolution of protein-coding genes is discussed.
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Projections of Global Mortality and Burden of Disease from 2002 to 2030

TL;DR: These projections represent a set of three visions of the future for population health, based on certain explicit assumptions, which enable us to appreciate better the implications for health and health policy of currently observed trends, and the likely impact of fairly certain future trends.
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Non-coding RNAs in human disease

TL;DR: Dysregulation of these ncRNAs is being found to have relevance not only to tumorigenesis, but also to neurological, cardiovascular, developmental and other diseases, and there is great interest in therapeutic strategies to counteract these perturbations.
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Overview of MicroRNA Biogenesis, Mechanisms of Actions, and Circulation.

TL;DR: An update on canonical and non-canonical miRNA biogenesis pathways and various mechanisms underlying miRNA-mediated gene regulations and the current knowledge of the dynamics of miRNA action and of the secretion, transfer, and uptake of extracellular miRNAs is provided.
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MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins

TL;DR: Evidence that high-density lipoprotein (HDL) transports endogenous miRNAs and delivers them to recipient cells with functional targeting capabilities is presented, indicating that HDL participates in a mechanism of intercellular communication involving the transport and delivery of miRNA.
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