The role of sex in the genomics of human complex traits
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Cites background from "The role of sex in the genomics of ..."
...Many traits, including disease risk, differ by sex and some of that may be partly genetic (78)....
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Cites background from "The role of sex in the genomics of ..."
..., Science 369, eaba3066 (2020) 11 September 2020 9 of 13 Adipose – Subcutaneous (6)...
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...These sex differences have been variously attributed to hormones, sex chromosomes, genotype × sex effects, differences in behavior, and differences in environmental exposures (6), but the mechanisms and underlying biology of the sex differences remain largely unknown....
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...Although we identified a set of X-linked geneswith sex-biased expression acrossmany tissues, the overall sharing of sex-biased expression among tissues was strongly skewed Oliva et al., Science 369, eaba3066 (2020) 11 September 2020 8 of 13 RESEARCH | GENETIC VARIATION Oliva et al., Science 369, eaba3066 (2020) 11 September 2020 9 of 13 Adipose – Subcutaneous (6) Artery – Aorta (1) Brain – Cerebellar Hemisphere (1) Breast – Mammary Tissue (49) Liver (3) Muscle – Skeletal (13) Skin –...
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