Journal ArticleDOI
The Syndrome of Asplenia, Pneumococcal Sepsis, and Disseminated Intravascular Coagulation
Alan L. Bisno,John C. Freeman +1 more
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Dseminated intravascular coagulation with Waterhouse-Friderichsen syndrome occurred during the course of fatal pneumococcal sepsis in a previously healthy woman and at postmortem examinatio...Abstract:
Disseminated intravascular coagulation with Waterhouse-Friderichsen syndrome occurred during the course of fatal pneumococcal sepsis in a previously healthy woman. At postmortem examinatio...read more
Citations
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Journal ArticleDOI
The Association Between Idiopathic Hemolytic Uremic Syndrome and Infection by Verotoxin-Producing Escherichia coli
TL;DR: A significant association exists between idiopathic HUS and infection by VTEC and the detection of free-fecal VT was the most important procedure for the early diagnosis of this infection.
Journal ArticleDOI
Postsplenectomy sepsis and its mortality rate: actual versus perceived risks.
TL;DR: It is shown that severe infection after splenectomy for benign disease is very uncommon except in infants and children below the age of 5 years and that children are reported to be no more susceptible to pneumococcal sepsis than to infection caused by any other organism.
Journal ArticleDOI
Autoimmune thrombocytopenic purpura
TL;DR: Adult autoimmune throbocytopenic purpura (ATP) is a platelet disorder that develops in certain individuals with a genetic as well as sex (female) predisposition following an environment event, which leads to the rapid clearance and destruction of opsonized platelets by the reticuloendothelial system, particularly the spleen.
Journal ArticleDOI
Splenic arterial interventions: anatomy, indications, technical considerations, and potential complications.
David C. Madoff,Alban Denys,Michael J. Wallace,Ravi Murthy,Sanjay Gupta,Edmund P. Pillsbury,Kamran Ahrar,Bertrand Bessoud,Marshall E. Hicks +8 more
TL;DR: Clinicians must be familiar with the splenic vascular anatomy, the indications and contraindications for performing interventional procedures, the technical considerations involved, and the potential use of other interventional techniques, such as radiofrequency ablation, in combination with splenic arterial interventions.
Journal ArticleDOI
Asplenic-hyposplenic overwhelming sepsis: postsplenectomy sepsis revisited.
Katrine Hansen,Don B. Singer +1 more
TL;DR: Surgeons have adopted techniques to save as much splenic tissue as possible and some splenic functions have been preserved, but conservative surgery has not provided total protection against overwhelming infection, and pathologists should comment on the risk of overwhelming sepsis when spleens are processed as surgical specimens.
References
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Journal ArticleDOI
Pneumococcal bacteremia with especial reference to bacteremic pneumococcal pneumonia.
Robert Austrian,Jerome Gold +1 more
TL;DR: Twenty-five years have elapsed since the subject of pneumococcal bacteremia has been reviewed, and in that period many changes have taken place both in the treatment of this disorder and in the research into its causes.
Journal ArticleDOI
Splenic studies. I. Susceptibility to infection after splenectomy performed in infancy.
Harold King,Harris B. Shumacker +1 more
Journal ArticleDOI
Hazard of overwhelming infection after splenectomy in childhood.
TL;DR: There should be little doubt that splenectomy may alter the ability to prevent or to suppress some infections in a child, however, the extent to which this change is clinically significant has been a source of continuing controversy.
Journal ArticleDOI
Deficiency of Pneumococcal Serum Opsonizing Activity in Sickle-Cell Disease
TL;DR: Serum opsonizing activity for salmonella was comparable in patients with sickle-cell disease and controls, although much of the activity was heat stable, and Hemolytic complement activity was similar in both groups of children.
Journal Article
The Formation of Circulating Antibody in the Splenec Tomized Human Being Following Intravenous Injection of Heterologous Erythrocytes
TL;DR: Sixteen control and fourteen splenectomized patients were given a single intravenous injection of 1.0 ml of a 2.0 per cent suspension of washed sheep erythrocytes and responded with a significant rise in antibody titer between nine to fourteen days after the injection.
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