The timing of prenatal exposure to maternal cortisol and psychosocial stress is associated with human infant cognitive development.
Reads0
Chats0
TLDR
Elevated levels of maternal cortisol and pregnancy-specific anxiety have programming influences on the developing fetus and are associated with lower 12-month mental development scores.Abstract:
The consequences of prenatal maternal stress for development were examined in 125 full-term infants at 3, 6, and 12 months of age. Maternal cortisol and psychological state were evaluated 5 times during pregnancy. Exposure to elevated concentrations of cortisol early in gestation was associated with a slower rate of development over the 1st year and lower mental development scores at 12 months. Elevated levels of maternal cortisol late in gestation, however, were associated with accelerated cognitive development and higher scores at 12 months. Elevated levels of maternal pregnancy-specific anxiety early in pregnancy were independently associated with lower 12-month mental development scores. These data suggest that maternal cortisol and pregnancy-specific anxiety have programming influences on the developing fetus.read more
Citations
More filters
Journal ArticleDOI
Anxiety, depression and stress in pregnancy: implications for mothers, children, research, and practice.
TL;DR: This body of evidence, and the developing consensus regarding biological and behavioral mechanisms, sets the stage for a next era of psychiatric and collaborative interdisciplinary research on pregnancy to reduce the burden of maternal stress, depression, and anxiety in the perinatal period.
Journal ArticleDOI
Children's Brain Development Benefits from Longer Gestation
Elysia Poggi Davis,Claudia Buss,L. Tugan Muftuler,Kevin Head,Anton N. Hasso,Deborah A. Wing,Calvin J. Hobel,Curt A. Sandman +7 more
TL;DR: It is demonstrated that even modest decreases in the duration of gestation can exert profound and lasting effects on neurodevelopment for both term and preterm infants and may contribute to long-term risk for health and disease.
Journal ArticleDOI
Prenatal developmental origins of behavior and mental health: The influence of maternal stress in pregnancy
Bea Van den Bergh,Marion I. van den Heuvel,Marius Lahti,Marijke A. K. A. Braeken,Susanne R. de Rooij,Sonja Entringer,Dirk Hoyer,Tessa J. Roseboom,Katri Räikkönen,Suzanne King,Matthias Schwab +10 more
TL;DR: This review systematically analyzes the available human studies to identify harmful stressors, vulnerable periods during pregnancy, specificities in the outcome and biological correlates of the relation between maternal stress and offspring outcome.
Journal ArticleDOI
Influence of maternal obesity on the long-term health of offspring.
Keith M. Godfrey,Rebecca M. Reynolds,Susan L. Prescott,Moffat J. Nyirenda,Moffat J. Nyirenda,Vincent W. V. Jaddoe,Johan G. Eriksson,Birit F.P. Broekman,Birit F.P. Broekman,Birit F.P. Broekman +9 more
TL;DR: There is an urgent need for studies on causality, underlying mechanisms, and effective interventions to reverse the epidemic of obesity in women of childbearing age and to mitigate consequences for offspring.
Journal ArticleDOI
Child development in the context of adversity: experiential canalization of brain and behavior.
Clancy Blair,C. Cybele Raver +1 more
TL;DR: The effects of poverty-related adversity on child development is examined, drawing upon psychobiological principles of experiential canalization and the biological embedding of experience to consider adaptive processes in response to adversity as an aspect of children's development.
References
More filters
Manual for the State-Trait Anxiety Inventory
TL;DR: The STAI as mentioned in this paper is an indicator of two types of anxiety, the state and trait anxiety, and measure the severity of the overall anxiety level, which is appropriate for those who have at least a sixth grade reading level.
Journal ArticleDOI
A global measure of perceived stress.
TL;DR: The Perceived Stress Scale showed adequate reliability and, as predicted, was correlated with life-event scores, depressive and physical symptomatology, utilization of health services, social anxiety, and smoking-reduction maintenance and was a better predictor of the outcome in question than were life- event scores.
Book
Hierarchical Linear Models: Applications and Data Analysis Methods
TL;DR: The Logic of Hierarchical Linear Models (LMLM) as discussed by the authors is a general framework for estimating and hypothesis testing for hierarchical linear models, and it has been used in many applications.
Journal ArticleDOI
Hierarchical Linear Models: Applications and Data Analysis Methods.
TL;DR: This chapter discusses Hierarchical Linear Models in Applications, Applications in Organizational Research, and Applications in the Study of Individual Change Applications in Meta-Analysis and Other Cases Where Level-1 Variances are Known.
Book
Applied Longitudinal Data Analysis
Judith D. Singer,John B. Willett +1 more
TL;DR: In this paper, a framework for investigating change over time is presented, where the multilevel model for change is introduced and a framework is presented for investigating event occurrence over time.