The Ubiquitin Code
Citations
913 citations
Cites background from "The Ubiquitin Code"
...SUMO-specific enzymes attach SUMO in an ATP-dependent enzymatic cascade that resembles ubiquitylation (9)....
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...Whether SUMO chains exhibit similarly diverse signaling properties as ubiquitin chains (9) requires further investigation....
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889 citations
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Cites background from "The Ubiquitin Code"
...Ubiquitination can affect proteins in different ways: it can tag proteins for degradation via the proteasome, change their cellular location, and promote or prevent interactions of proteins (Komander and Rape, 2012)....
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794 citations
References
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"The Ubiquitin Code" refers background in this paper
...Unanchored ubiquitin chains are generated during ubiquitin biosynthesis as products of the UBB and UBC genes (95), by DUBs that internally cleave ubiquitin chains or release entire chains from substrates (96), or by ubiquitylation enzymes that synthesize unanchored polymers for signal transduction (97, 98)....
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2,379 citations
"The Ubiquitin Code" refers background in this paper
...RBR E3s display linkage specificity: The linear ubiquitin chain assembly complex (LUBAC) assembles Met1-linked chains (8, 76–78), and parkin catalyzes monoubiquitylation as well as Lys63-, Lys48-, and Lys27-linked chain formation (79, 80)....
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2,359 citations
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"The Ubiquitin Code" refers background in this paper
...Lys63-linked chains activate IKK by promoting its binding to the upstream TAK1 kinase complex (181)....
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