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Journal ArticleDOI

The worldwide incidence of preterm birth: a systematic review of maternal mortality and morbidity

TL;DR: Developing countries, especially those in Africa and southern Asia, incur the highest burden in terms of absolute numbers, although a high rate is also observed in North America.
Abstract: Resumen Incidencia mundial de parto prematuro: revision sistematica de la morbilidad y mortalidad maternas Objetivo Analizar las tasas de prematuridad a nivel mundial para evaluar la incidencia de este problema de salud publica, determinar la distribucion regional de los partos prematuros y profundizar en el conocimiento de las actuales estrategias de evaluacion.Metodos Los datos utilizados sobre las tasas de prematuridad a nivel mundial se extrajeron a lo largo de una revision sistematica anterior de datos publicados e ineditos sobre la mortalidad y morbilidad maternas notificados entre 1997 y 2002. Esos datos se complementaron mediante una busqueda que abarco el periodo 2003–2007. Las tasas de prematuridad de los paises sin datos se estimaron mediante modelos de regresion multiple especificos para cada region.Resultados Estimamos que en 2005 se registraron 12,9 millones de partos prematuros, lo que representa el 9,6% de todos los nacimientos a nivel mundial. Aproximadamente 11 millones (85%) de ellos se concentraron en Africa y Asia, mientras que en Europa y America del Norte (excluido Mexico) se registraron 0,5 millones en cada caso, y en America Latina y el Caribe, 0,9 millones. Las tasas mas elevadas de prematuridad se dieron en Africa y America del Norte (11,9% y 10,6% de todos los nacimientos, respectivamente), y las mas bajas en Europa (6,2%).Conclusion El parto prematuro es un problema de salud perinatal importante en todo el mundo. Los paises en desarrollo, especialmente de Africa y Asia meridional, son los que sufren la carga mas alta en terminos absolutos, pero en America del Norte tambien se observa una tasa elevada. Es necesario comprender mejor las causas de la prematuridad y obtener estimaciones mas precisas de la incidencia de ese problema en cada pais si se desea mejorar el acceso a una atencion obstetrica y neonatal eficaz.

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Citations
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Journal ArticleDOI
TL;DR: Worldwide, regional, and national estimates of preterm birth rates for 184 countries in 2010 with time trends for selected countries are reported, and a quantitative assessment of the uncertainty surrounding these estimates is provided.

3,742 citations

Journal ArticleDOI
TL;DR: The designations employed and the presentation of the material in this publication do not imply the expression of any opinion whatsoever on the part of UNEP or WHO concerning the legal status of any country, territory, city or area or of its authorities, or concerning the delimitation of its frontiers or boundaries.

1,192 citations

Book
14 Oct 2009
TL;DR: Identifying factors associated with patient’s risk for hospitalization or emergency department visits in home health care May 2021 Podium Presentation.

787 citations

Journal ArticleDOI
TL;DR: The efficacy and safety of using micronized vaginal progesterone gel to reduce the risk of preterm birth and associated neonatal complications in women with a sonographic short cervix is determined.
Abstract: Objectives Women with a sonographic short cervix in the mid-trimester are at increased risk for preterm delivery. This study was undertaken to determine the efficacy and safety of using micronized vaginal progesterone gel to reduce the risk of preterm birth and associated neonatal complications in women with a sonographic short cervix. Methods This was a multicenter, randomized, doubleblind, placebo-controlled trial that enrolled asymptomatic

777 citations

References
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Book
01 Jan 1966
TL;DR: In this article, the Straight Line Case is used to fit a straight line by least squares, and the Durbin-Watson Test is used for checking the straight line fit.
Abstract: Basic Prerequisite Knowledge. Fitting a Straight Line by Least Squares. Checking the Straight Line Fit. Fitting Straight Lines: Special Topics. Regression in Matrix Terms: Straight Line Case. The General Regression Situation. Extra Sums of Squares and Tests for Several Parameters Being Zero. Serial Correlation in the Residuals and the Durbin--Watson Test. More of Checking Fitted Models. Multiple Regression: Special Topics. Bias in Regression Estimates, and Expected Values of Mean Squares and Sums of Squares. On Worthwhile Regressions, Big F's, and R 2 . Models Containing Functions of the Predictors, Including Polynomial Models. Transformation of the Response Variable. "Dummy" Variables. Selecting the "Best" Regression Equation. Ill--Conditioning in Regression Data. Ridge Regression. Generalized Linear Models (GLIM). Mixture Ingredients as Predictor Variables. The Geometry of Least Squares. More Geometry of Least Squares. Orthogonal Polynomials and Summary Data. Multiple Regression Applied to Analysis of Variance Problems. An Introduction to Nonlinear Estimation. Robust Regression. Resampling Procedures (Bootstrapping). Bibliography. True/False Questions. Answers to Exercises. Tables. Indexes.

18,952 citations

Journal ArticleDOI
TL;DR: A short cervical length and a raised cervical-vaginal fetal fibronectin concentration are the strongest predictors of spontaneous preterm birth.

6,275 citations

01 Jan 1998

5,511 citations

Journal ArticleDOI
TL;DR: The evidence indicating that the pathological processes implicated in the preterm parturition syndrome include: intrauterine infection/inflammation; uterine ischaemia; (3) uterine overdistension; (4) abnormal allograft reaction; (5) allergy; (6) cervical insufficiency; and (7) hormonal disorders (progesterone related and corticotrophin‐releasing factor related).

1,193 citations

Journal ArticleDOI
16 Sep 2004-BMJ
TL;DR: Over the past 20-30 years advances in perinatal care have improved outcomes for infants born after short gestations, but there is still uncertainty and incomplete recording of estimates of gestation in developed countries.
Abstract: Preterm birth is a major challenge in perinatal health care. Most perinatal deaths occur in preterm infants, and preterm birth is an important risk factor for neurological impairment and disability. Preterm birth not only affects infants and their families—providing care for preterm infants, who may spend several months in hospital, has increasing cost implications for health services. Preterm birth is the delivery of a baby before 37 completed weeks' gestation. Most mortality and morbidity affects “very preterm” infants (those born before 32 weeks' gestation), and especially “extremely preterm” infants (those born before 28 weeks of gestation). Definitions of preterm live births by completed weeks of gestation Over the past 20-30 years advances in perinatal care have improved outcomes for infants born after short gestations. The number of weeks of completed gestation that defines whether a birth is preterm rather than a fetal loss has become smaller. In 1992 the boundary that required registration as a preterm live birth in the United Kingdom was lowered from 28 completed weeks' gestation to 24 weeks' gestation. This boundary varies internationally, however, from about 20 to 24 weeks. Some classification of fetal loss, still birth, and early neonatal death for these very short gestations may be unreliable. Even in developed countries, there is often uncertainty and incomplete recording of estimates of gestation. In most of the United Kingdom data on birth weight data but not on gestational age are collected routinely. Although some concordance exists between the categories of birth weight and gestational age, they are not interchangeable. The categories for birth weight are: Only around two thirds of …

817 citations