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Journal ArticleDOI

Therapeutic and Medicinal Uses of Aloe vera: A Review

08 Nov 2013-Pharmacology & Pharmacy (Scientific Research Publishing)-Vol. 04, Iss: 8, pp 599-610
TL;DR: The plant Aloe vera is used in Ayurvedic, Homoeopathic and Allopathic streams of medicine, and not only tribal community but also most of the people for food and medicine.
Abstract: The plant Aloe vera is used in Ayurvedic, Homoeopathic and Allopathic streams of medicine, and not only tribal community but also most of the people for food and medicine. The plant leaves contains numerous vitamins, minerals, enzymes, amino acids, natural sugars and other bioactive compounds with emollient, purgative, anti-microbial, anti inflammatory, antioxidant, aphrodisiac, anti-helmenthic, antifungal, antiseptic and cosmetic values for health care. This plant has potential to cure sunburns, burns and minor cuts, and even skin cancer. The external use in cosmetic primarily acts as skin healer and prevents injury of epithelial tissues, cures acne and gives a youthful glow to skin, also acts as extremely powerful laxative.
Citations
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Journal Article
TL;DR: The aim of the present review is to understand the knowledge of the medicinal plants as a future source of herbal drugs in India.
Abstract: India has a long history and strong base for Ayurveda, which is the traditional herbal medical system. Herbal plants play an important role in preventing and treating of human diseases. People have been using plants as a traditional medicine for thousand years ago. Plants have been associated with the development of human civilization around the whole world. However, plants are considered as rich sources of phytochemical ingredients which enable to have medicinal value. Medicinal plants are a potential source for the development of new herbal drugs. In the 21st century, the pharmacological effects of medicinal plants have been considered as a promising future drug/medicine for the management of health care. In recent years, there has been a resurgence of interest to rediscover medicinal plants as a source of potential drug candidate. Therefore, the aim of the present review is to understand the knowledge of the medicinal plants as a future source of herbal drugs.

235 citations


Cites background from "Therapeutic and Medicinal Uses of A..."

  • ...[40] Tulsi Apigenin, Taxol and Ursolic acid, Citral Antidiabetic, Hepatoprotective anti-bacterial, antifungal, anti-pyretic and anti-cancer properties...

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Journal ArticleDOI
19 Oct 2016-PeerJ
TL;DR: The results indicated that AgNPs@AV can be effectively utilized in pharmaceutical, biotechnological and biomedical applications and showed that the antibacterial effect of this hybrid nanomaterial was sufficient that it could be used to inhibit pathogenic bacteria.
Abstract: Background There is worldwide interest in silver nanoparticles (AgNPs) synthesized by various chemical reactions for use in applications exploiting their antibacterial activity, even though these processes exhibit a broad range of toxicity in vertebrates and invertebrates alike. To avoid the chemical toxicity, biosynthesis (green synthesis) of metal nanoparticles is proposed as a cost-effective and environmental friendly alternative. Aloe vera leaf extract is a medicinal agent with multiple properties including an antibacterial effect. Moreover the constituents of aloe vera leaves include lignin, hemicellulose, and pectins which can be used in the reduction of silver ions to produce as AgNPs@aloe vera (AgNPs@AV) with antibacterial activity. Methods AgNPs were prepared by an eco-friendly hydrothermal method using an aloe vera plant extract solution as both a reducing and stabilizing agent. AgNPs@AV were characterized using XRD and SEM. Additionally, an agar well diffusion method was used to screen for antimicrobial activity. MIC and MBC were used to correlate the concentration of AgNPs@AV its bactericidal effect. SEM was used to investigate bacterial inactivation. Then the toxicity with human cells was investigated using an MTT assay. Results The synthesized AgNPs were crystalline with sizes of 70.70 ± 22-192.02 ± 53 nm as revealed using XRD and SEM. The sizes of AgNPs can be varied through alteration of times and temperatures used in their synthesis. These AgNPs were investigated for potential use as an antibacterial agent to inhibit pathogenic bacteria. Their antibacterial activity was tested on S. epidermidis and P. aeruginosa. The results showed that AgNPs had a high antibacterial which depended on their synthesis conditions, particularly when processed at 100 oC for 6 h and 200 oC for 12 h. The cytotoxicity of AgNPs was determined using human PBMCs revealing no obvious cytotoxicity. These results indicated that AgNPs@AV can be effectively utilized in pharmaceutical, biotechnological and biomedical applications. Discussion Aloe vera extract was processed using a green and facile method. This was a hydrothermal method to reduce silver nitrate to AgNPs@AV. Varying the hydrothermal temperature provided the fine spherical shaped nanoparticles. The size of the nanomaterial was affected by its thermal preparation. The particle size of AgNPs could be tuned by varying both time and temperature. A process using a pure AG phase could go to completion in 6 h at 200 oC, whereas reactions at lower temperatures required longer times. Moreover, the antibacterial effect of this hybrid nanomaterial was sufficient that it could be used to inhibit pathogenic bacteria since silver release was dependent upon its particle size. The high activity of the largest AgNPs might have resulted from a high concentration of aloe vera compounds incorporated into the AgNPs during hydrothermal synthesis.

227 citations


Cites background from "Therapeutic and Medicinal Uses of A..."

  • ...Various natural ligands can interact with microbial membrane such as saponin, tannin, terpenoids, and flavonoids in the aloe vera (Griffin et al., 1999; Sahu et al., 2013)....

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Journal ArticleDOI
TL;DR: This book is intended as a reference work for pharmacists, doctors and other health-care professionals to assist them in the provision of advice on the use of health remedies (herbal products) to members of the public.

185 citations

Journal ArticleDOI
TL;DR: An extensive review on Aloe vera was carried out, including its main uses, components (both nutrients and bioactives), biological activities, and applications, and future trends were assessed.
Abstract: Background There are many plants with interesting pharmaceutical activities but Aloe vera is probably the most applied medicinal plant worldwide. Since biblical times, aloe has been used for its purgative effect, skin disorders healing and beauty treatments. Scope and approach For this study, an extensive review on Aloe vera was carried out, including its main uses, components (both nutrients and bioactives), biological activities, and applications. Future trends were also assessed. Key findings and conclusions Aloe possesses numerous activities including, anticancer, antioxidant, antimicrobial, antiallergic, anti-inflammatory, immunomodulatory, hepatoprotective, antiulcer and antidiabetic. Some of these activities are due to the presence of polysaccharides (acemamman; glucomannan). A wide variety of commercial products based on Aloe vera are available on the market. However, the knowledge of the relationship between biological and therapeutic properties and its components has to be clearly defined in order to know the exact mechanism of action to develop effective new products, namely pharmaceuticals. The knowledge of the factors that affect Aloe vera variability, such as processing conditions, is also of great importance to be able to standardize the final products.

128 citations

Journal ArticleDOI
TL;DR: In this work, the future of A. vera as effective antioxidants is primarily discussed and expected trends are summarised, and the bioactive components and the health-promoting effects of A., vera are investigated.
Abstract: Many studies have proved that bioactive components of Aloe vera have an anti-inflammatory effect and support lipid and carbohydrate metabolism, helping to maintain normal sugar and cholesterol levels in blood and normal body weight. When aloe is applied externally, it accelerates the regeneration of the damaged skin. Aloe contains antioxidants, which may increase the shelf-life and nutritional value of food; therefore, it is widely used in cosmetic, pharmaceutical and food industry. An antioxidant activity was shown for leaf’s skin, flowers and gel of aloe. In this work the future of A. vera as effective antioxidants is primarily discussed and expected trends are summarised. Furthermore, the bioactive components and the health-promoting effects of A. vera are investigated.

122 citations

References
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Journal ArticleDOI
TL;DR: On pharmacology and the rational use of drugs, 42 authors share the herculean task of reviewing the flood of recent literature under single or dual authorship and each chapter offers a complete and up-to-date review.

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TL;DR: Part 1 Monographs on drugs and ancillary substances, Supplementary drugs and other substances, and Indexes - directory of manufacturers.

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TL;DR: Reading medical laboratory manual for tropical countries is also a way as one of the collective books that gives many advantages.
Abstract: No wonder you activities are, reading will be always needed. It is not only to fulfil the duties that you need to finish in deadline time. Reading will encourage your mind and thoughts. Of course, reading will greatly develop your experiences about everything. Reading medical laboratory manual for tropical countries is also a way as one of the collective books that gives many advantages. The advantages are not only for you, but for the other peoples with those meaningful benefits.

1,637 citations


Additional excerpts

  • ...coccodes [125,126]....

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Book
01 Feb 1996
TL;DR: In this article, a general introduction to the monographs general references monographs is given, along with a 20 appendices list of the main monographs and their corresponding appendices.
Abstract: How to use this book introduction to the monographs general references monographs. 20 appendices.

1,091 citations