Therapeutic potential of resveratrol: the in vivo evidence.
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...RSV is a natural polyphenolic compound mainly found in the skin of grapes and is well known for its phytoestrogenic and antioxidant properties (Baur and Sinclair, 2006)....
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...Admittedly, RSV is reported to have pleiotropic properties, including the activation of signaling pathways involving AMPK, thyroid hormone, and estrogen (Baur and Sinclair, 2006; Baur et al., 2006)....
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...Resveratrol has been shown to induce the expression of eNOS when tested either alone (205, 239) or in combination with a statin (240), albeit in one rat study it failed to induce eNOS expression (241)....
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...CR has been shown to reduce tumor formation (203), as has resveratrol (204, 205), but it was unclear whether SIRT1 overexpression would result in more or fewer tumors....
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References
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...2 ) have shown that resveratrol can prevent or slow the progression of a wide variety of illnesses, including cance...
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...Resveratrol and heart disease Regular consumption of red wine is often credited as the explanation for the 'French Paradox...
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3,412 citations
"Therapeutic potential of resveratro..." refers background in this paper
..., whereas prostacyclin, which is synthesized by COX2 in vascular endothelial cells, is an antiplatelet aggregator and a vasodilato...
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