Thrombo-inflammation response to Tocilizumab in COVID-19.
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4,408 citations
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16,635 citations
"Thrombo-inflammation response to To..." refers background in this paper
...Coagulopathy is now appreciated as a significant component of morbidity in COVID-19(1-3), and this may be due pulmonary vascular endotheliopathy and deposition fibrin thrombi in small and large vessels of the lung (19)....
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...Whereas most patients experience few if any symptoms, a relevant proportion develop severe respiratory disease, inflammation in other organs, and a hypercoagulable state (1-3)....
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6,850 citations
"Thrombo-inflammation response to To..." refers background in this paper
...Coagulopathy is now appreciated as a significant component of morbidity in COVID-19(1-3), and this may be due pulmonary vascular endotheliopathy and deposition fibrin thrombi in small and large vessels of the lung (19)....
[...]
4,331 citations
"Thrombo-inflammation response to To..." refers background in this paper
...Coagulopathy is now appreciated as a significant component of morbidity in COVID-19(1-3), and this may be due pulmonary vascular endotheliopathy and deposition fibrin thrombi in small and large vessels of the lung (19)....
[...]
...Whereas most patients experience few if any symptoms, a relevant proportion develop severe respiratory disease, inflammation in other organs, and a hypercoagulable state (1-3)....
[...]
3,286 citations
"Thrombo-inflammation response to To..." refers background in this paper
...SARS-CoV-2 suppresses the initial type I Interferon response that is critical for control of viral infections (4, 8)....
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...An excessive immune response to various viral infections has been associated with hyperinflammation and multi-organ immune-mediated pathology (4)....
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