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Ti based biomaterials, the ultimate choice for orthopaedic implants – A review

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TLDR
In this paper, the influence of alloy chemistry, thermomechanical processing and surface condition on these properties is discussed and various surface modification techniques to achieve superior biocompatibility, higher wear and corrosion resistance.
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This article is published in Progress in Materials Science.The article was published on 2009-05-01. It has received 4113 citations till now. The article focuses on the topics: Biomaterial.

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Citations
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Perspectives on Titanium Science and Technology

TL;DR: In this paper, the complexity and variety of fundamental phenomena in this material system with a focus on phase transformations and mechanical behaviour are discussed. And the challenges that lie ahead in achieving these goals are delineated.
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Metallic implant biomaterials

TL;DR: In this article, the most critical challenges for metallic implant biomaterials are summarized, with emphasis on the most promising approaches and strategies, and the properties that affect biocompatibility and mechanical integrity are discussed in detail.
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Review on titanium and titanium based alloys as biomaterials for orthopaedic applications.

TL;DR: Various attempts to improve upon these properties like different processing routes, surface modifications have been inculcated in the paper to provide an insight into the extent of research and effort that has been put into developing a highly superior titanium orthopaedic implant.
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New Developments of Ti-Based Alloys for Biomedical Applications

TL;DR: Efforts have been made to reveal the latest scenario of bulk and porous Ti-based materials for biomedical applications, emphasizing their current status, future opportunities and obstacles for expanded applications.
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Mussel-Inspired Polydopamine Coating as a Universal Route to Hydroxyapatite Crystallization

TL;DR: A universal biomineralization route, called polydopamine‐assisted hydroxyapatite formation (pHAF), that can be applied to virtually any type and morphology of scaffold materials is demonstrated and can be an innovative foundation for future tissue engineering.
References
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Book

The Biomedical Engineering Handbook

TL;DR: Physiological systems bioelectric phenomena biomechanics biomaterials biosensors biomedical signal analysis imaging medical instruments and devices biological effects of non-ionizing biotechnology tissue engineering human performance engineering physiological modelling, simulation and control clinical engineering and artificial intelligence.
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Mechanical properties of biomedical titanium alloys

TL;DR: Titanium alloys are expected to be much more widely used for implant materials in the medical and dental fields because of their superior biocompatibility, corrosion resistance and specific strength compared with other metallic implant materials.
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Influence of surface characteristics on bone integration of titanium implants. A histomorphometric study in miniature pigs.

TL;DR: The extent of bone-implant interface is positively correlated with an increasing roughness of the implant surface, and hydroxylapatite (HA)-coated implants with 60-70% showed signs of resorption.
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Biomedical applications of polymer-composite materials: a review

TL;DR: An overview of various biomedical applications of polymer-composite materials reported in the literature over the last 30 years is presented in this paper, where the critical issues and scientific challenges that require further research and development of polymer composite materials for their increased acceptance in the biomedical industry are also highlighted.
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Enhanced functions of osteoblasts on nanophase ceramics

TL;DR: The results of the present study provided the first evidence of enhanced long-term (on the order of days to weeks) functions of osteoblasts cultured on nanophase ceramics, and clearly represent a unique and promising class of orthopaedic/dental implant formulations with improved osseointegrative properties.
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