Journal ArticleDOI
Tianeptine, an atypical pharmacological approach to depression
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TLDR
Tianeptine as a glutamatergic modulator, among other mechanisms, allows us to approach depression from a different point of view than other antidepressants, to clarify that in depression there is more than monoamines.About:
This article is published in Revista de Psiquiatría y Salud Mental.The article was published on 2019-07-01. It has received 10 citations till now. The article focuses on the topics: Tianeptine & Antidepressant.read more
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Journal ArticleDOI
Depression in Alzheimer's Disease: A Delphi Consensus on Etiology, Risk Factors, and Clinical Management.
Luis Agüera-Ortiz,Rocío García-Ramos,Francisco J. Grandas Pérez,Jorge López-Álvarez,José Manuel Montes Rodríguez,F. Javier Olazarán Rodríguez,Javier Olivera Pueyo,Carmelo Pelegrín Valero,Jesús Porta-Etessam +8 more
TL;DR: In this paper, a survey of expert opinions on dementia and depressed patient management was conducted to reduce heterogeneity in everyday practice. And the most relevant findings were that depression in the elderly was considered an early sign (prodromal) and/or a dementia risk factor, so routine cognitive check-ups in depressed patients should be adopted, aided by clinical scales and information from relatives.
Journal ArticleDOI
Changes in Hippocampal Plasticity in Depression and Therapeutic Approaches Influencing These Changes.
Wenbo Xu,Xiaoxiao Yao,Fangyi Zhao,Haisheng Zhao,Ziqian Cheng,Wei Yang,Ranji Cui,Songbai Xu,Bingjin Li +8 more
TL;DR: The latest research is summarized, focusing on changes in the plasticity of hippocampal neurons and glial cells in depression and the role of BDNF in the changes in hippocampal plasticity in depression, as well as caloric restriction and mitochondrial plasticity.
Journal ArticleDOI
Management of cognitive impairment in bipolar disorder: a systematic review of randomized controlled trials.
Jocelyn K. Tamura,Isabelle P. Carvalho,Lui M W Leanna,Jia Nuo Feng,Joshua D. Rosenblat,Rodrigo B. Mansur,Yena Lee,Yena Lee,Danielle S. Cha,Kayla M. Teopiz,Zara Ahmad,Flora Nasri,Jiin Kim,Roger S. McIntyre +13 more
TL;DR: A systematic search was conducted on PubMed, PsycInfo, Cochrane, clinicaltrialsgov, and Embase databases for blinded or open-label randomized controlled trials evaluating the pro-cognitive effects of pharmacological, neurostimulation, or psychological interventions for bipolar disorder.
Journal ArticleDOI
Potencial abuso y dependencia de tianeptina. Revisión a propósito de un caso
TL;DR: In this article, el caso de un varon de 47 anos con diagnosticos de trastorno bipolar tipo ii, trastornos limite de personalidad and trastorón por uso sustancias, presentaba una dependencia a tianeptina, de la que llego a consumir 1.125mg al dia.
Journal ArticleDOI
How Antidepressant Drugs Affect the Antielectroshock Action of Antiseizure Drugs in Mice: A Critical Review.
TL;DR: In this article, a review of the interactions between antidepressants and antielectro-shock drugs was conducted in mice with maximal electroshock (MES) in a seizure model.
References
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The catecholamine hypothesis of affective disorders: a review of supporting evidence
TL;DR: The "catecholamine hypothesis of affective disorders" as discussed by the authors suggests that depression is associated with an absolute or relative decrease in catecholamines, particularly norepinephrine, available at central adrenergic receptor sites.
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A neurotrophic model for stress-related mood disorders.
TL;DR: Analysis of preclinical cellular and behavioral models of depression and antidepressant actions, as well as clinical neuroimaging and postmortem studies, are consistent with the hypothesis that decreased expression of BDNF and possibly other growth factors contributes to depression and that upregulation ofBDNF plays a role in the actions of antidepressant treatment.
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The corticosteroid receptor hypothesis of depression.
TL;DR: Mouse genetics, allowing for selective inactivation of genes relevant for HPA regulation and molecular pharmacology, dissecting the intracellular cascade of CR signaling, are the most promising future research fields, suited for identifying genes predisposing to depression.
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Chronic stress induces contrasting patterns of dendritic remodeling in hippocampal and amygdaloid neurons.
TL;DR: It is raised the possibility that certain forms of chronic stress, by affecting specific neuronal elements in the amygdala, may lead to behavioral manifestations of enhanced emotionality, and stress-induced structural plasticity in amygdala neurons may provide a candidate cellular substrate for affective disorders triggered by chronic stress.
Journal ArticleDOI
Driving AMPA Receptors into Synapses by LTP and CaMKII: Requirement for GluR1 and PDZ Domain Interaction
Yasunori Hayashi,Song-Hai Shi,José A. Esteban,Antonella Piccini,Jean Christophe Poncer,Roberto Malinow +5 more
TL;DR: Results show that LTP and CaMKII activity drive AMPA-Rs to synapses by a mechanism that requires the association between GluR1 and a PDZ domain protein.