Tracing the genetic origin of Europe's first farmers reveals insights into their social organization
Anna Szécsényi-Nagy,Anna Szécsényi-Nagy,Guido Brandt,Wolfgang Haak,Victoria Keerl,János Jakucs,Sabine Möller-Rieker,Kitti Köhler,Balázs Gusztáv Mende,Krisztián Oross,Tibor Marton,Anett Osztás,Viktória Kiss,Marc Fecher,György Pálfi,Erika Molnár,Katalin Sebők,András Czene,Tibor Paluch,Mario Šlaus,Mario Novak,Nives Pećina-Šlaus,Brigitta Ősz,Vanda Voicsek,Krisztina Somogyi,Gábor A. Tóth,Bernd Kromer,Eszter Bánffy,Kurt W. Alt +28 more
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TLDR
Comprehensive Y chromosomal and mitochondrial DNA population genetic analyses demonstrate a clear affinity of the early farmers to the modern Near East and Caucasus, tracing the expansion from that region through southeastern Europe and the Carpathian Basin into Central Europe.Abstract:
Farming was established in Central Europe by the Linearbandkeramik culture (LBK), a well-investigated archaeological horizon, which emerged in the Carpathian Basin, in today's Hungary. However, the...read more
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Journal ArticleDOI
Massive migration from the steppe was a source for Indo-European languages in Europe
Wolfgang Haak,Iosif Lazaridis,Nick Patterson,Nadin Rohland,Swapan Mallick,Bastien Llamas,Guido Brandt,Susanne Nordenfelt,Eadaoin Harney,Kristin Stewardson,Qiaomei Fu,Alissa Mittnik,Eszter Bánffy,Christos Economou,Michael Francken,Susanne Friederich,Rafael Garrido Pena,Fredrik Hallgren,Valery Khartanovich,Aleksandr Khokhlov,Michael Kunst,Pavel Kuznetsov,Harald Meller,Oleg Mochalov,Vayacheslav Moiseyev,Nicole Nicklisch,Sandra Pichler,Roberto Risch,Manuel Ángel Rojo Guerra,Christina Roth,Anna Szécsényi-Nagy,Joachim Wahl,Matthias Meyer,Johannes Krause,Dorcas Brown,David W. Anthony,Alan Cooper,Kurt W. Alt,David Reich +38 more
TL;DR: In this paper, the authors generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost 400,000 polymorphisms.
Journal ArticleDOI
Genome-wide patterns of selection in 230 ancient Eurasians
Iain Mathieson,Iosif Lazaridis,Iosif Lazaridis,Nadin Rohland,Nadin Rohland,Swapan Mallick,Swapan Mallick,Swapan Mallick,Nick Patterson,Songül Alpaslan Roodenberg,Eadaoin Harney,Eadaoin Harney,Kristin Stewardson,Kristin Stewardson,Daniel Fernandes,Mario Novak,Kendra Sirak,Kendra Sirak,Cristina Gamba,Cristina Gamba,Cristina Gamba,Eppie R. Jones,Bastien Llamas,Stanislav Dryomov,Joseph K. Pickrell,Juan Luis Arsuaga,José María Bermúdez de Castro,Eudald Carbonell,Fokke Gerritsen,Aleksandr Khokhlov,Pavel Kuznetsov,Marina Lozano,Harald Meller,Oleg Mochalov,Vayacheslav Moiseyev,Manuel Ángel Rojo Guerra,Jacob Roodenberg,Josep Maria Vergès,Johannes Krause,Johannes Krause,Alan Cooper,Kurt W. Alt,Kurt W. Alt,Dorcas Brown,David W. Anthony,Carles Lalueza-Fox,Wolfgang Haak,Wolfgang Haak,Ron Pinhasi,David Reich,David Reich,David Reich +51 more
TL;DR: A genome-wide scan for selection using ancient DNA is reported, capitalizing on the largest ancient DNA data set yet assembled: 230 West Eurasians who lived between 6500 and 300 bc, including 163 with newly reported data.
Journal ArticleDOI
The Beaker phenomenon and the genomic transformation of northwest Europe
Iñigo Olalde,Selina Brace,Morten E. Allentoft,Ian Armit,Kristian Kristiansen,Thomas J. Booth,Nadin Rohland,Swapan Mallick,Swapan Mallick,Swapan Mallick,Anna Szécsényi-Nagy,Alissa Mittnik,Alissa Mittnik,Eveline Altena,Mark Lipson,Iosif Lazaridis,Iosif Lazaridis,Thomas K. Harper,Nick Patterson,Nasreen Broomandkhoshbacht,Nasreen Broomandkhoshbacht,Yoan Diekmann,Zuzana Faltyskova,Daniel Fernandes,Daniel Fernandes,Daniel Fernandes,Matthew Ferry,Matthew Ferry,Eadaoin Harney,Peter de Knijff,Megan Michel,Megan Michel,Jonas Oppenheimer,Jonas Oppenheimer,Kristin Stewardson,Kristin Stewardson,Alistair Barclay,Kurt W. Alt,Kurt W. Alt,Corina Liesau,Patricia Ríos,Concepción Blasco,Jorge Vega de Miguel,Roberto Menduiña García,Azucena Avilés Fernández,Eszter Bánffy,Eszter Bánffy,Maria Bernabò-Brea,David Billoin,Clive Bonsall,Laura Bonsall,Tim Allen,Lindsey Büster,Sophie Carver,Laura Castells Navarro,Oliver E. Craig,Gordon Cook,Barry Cunliffe,Anthony Denaire,Kirsten Egging Dinwiddy,Natasha Dodwell,Michal Ernée,Christopher Evans,Milan Kuchařík,Joan Francès Farré,Chris Fowler,Michiel Gazenbeek,Rafael Garrido Pena,María Haber-Uriarte,Elżbieta Haduch,Gill Hey,Nick Jowett,Timothy D J Knowles,Ken Massy,Saskia Pfrengle,Philippe Lefranc,Olivier Lemercier,Arnaud Lefebvre,Arnaud Lefebvre,César Heras Martínez,Virginia Galera Olmo,Ana Bastida Ramírez,Joaquín Lomba Maurandi,Tona Majó,Jacqueline I. McKinley,Kathleen McSweeney,Balázs Gusztáv Mende,Alessandra Modi,Gabriella Kulcsár,Viktória Kiss,András Czene,Róbert Patay,Anna Endrődi,Kitti Köhler,Tamás Hajdu,Tamás Hajdu,Tamás Szeniczey,János Dani,Zsolt Bernert,Maya Hoole,Olivia Cheronet,Olivia Cheronet,Denise Keating,Petr Velemínský,Miroslav Dobeš,Francesca Candilio,Francesca Candilio,Fraser Brown,Raúl Flores Fernández,Ana-Mercedes Herrero-Corral,Sebastiano Tusa,Emiliano Carnieri,Luigi Lentini,Antonella Valenti,Alessandro Zanini,Clive Waddington,Germán Delibes,Elisa Guerra-Doce,Benjamin Neil,Marcus Brittain,Mike Luke,Richard Mortimer,Jocelyne Desideri,Marie Besse,Günter Brücken,Mirosław Furmanek,Agata Hałuszko,Maksym Mackiewicz,Artur Rapiński,Stephany Leach,Ignacio Soriano,Katina T. Lillios,João Luís Cardoso,João Luís Cardoso,Mike Parker Pearson,Piotr Włodarczak,T. Douglas Price,Pilar Prieto,Pierre-Jérôme Rey,Roberto Risch,Manuel Ángel Rojo Guerra,Aurore Schmitt,Joël Serralongue,Ana Maria Silva,Václav Smrčka,Luc Vergnaud,João Zilhão,João Zilhão,João Zilhão,David Caramelli,Thomas Higham,Mark G. Thomas,Douglas J. Kennett,Harry Fokkens,Volker M Heyd,Volker M Heyd,Alison Sheridan,Karl-Göran Sjögren,Philipp W. Stockhammer,Philipp W. Stockhammer,Johannes Krause,Ron Pinhasi,Ron Pinhasi,Wolfgang Haak,Wolfgang Haak,Ian Barnes,Carles Lalueza-Fox,David Reich,David Reich,David Reich +169 more
TL;DR: Genome-wide data from 400 Neolithic, Copper Age and Bronze Age Europeans is presented, finding limited genetic affinity between Beaker-complex-associated individuals from Iberia and central Europe, and excludes migration as an important mechanism of spread between these two regions.
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis,Iosif Lazaridis,Nick Patterson,Alissa Mittnik,Gabriel Renaud,Swapan Mallick,Swapan Mallick,Karola Kirsanow,Peter H. Sudmant,Joshua G. Schraiber,Joshua G. Schraiber,Sergi Castellano,Mark Lipson,Bonnie Berger,Bonnie Berger,Christos Economou,Ruth Bollongino,Qiaomei Fu,Kirsten I. Bos,Susanne Nordenfelt,Susanne Nordenfelt,Heng Li,Heng Li,Cesare de Filippo,Kay Prüfer,Susanna Sawyer,Cosimo Posth,Wolfgang Haak,Fredrik Hallgren,Elin Fornander,Nadin Rohland,Nadin Rohland,Dominique Delsate,Michael Francken,Jean-Michel Guinet,Joachim Wahl,George Ayodo,Hamza A. Babiker,Hamza A. Babiker,Graciela Bailliet,Elena Balanovska,Oleg Balanovsky,Ramiro Barrantes,Gabriel Bedoya,Haim Ben-Ami,Judit Bene,Fouad Berrada,Claudio M. Bravi,Francesca Brisighelli,George B.J. Busby,Francesco Calì,Mikhail Churnosov,David E. C. Cole,Daniel Corach,Larissa Damba,George van Driem,Stanislav Dryomov,Jean-Michel Dugoujon,Sardana A. Fedorova,Irene Gallego Romero,Marina Gubina,Michael F. Hammer,Brenna M. Henn,Tor Hervig,Ugur Hodoglugil,Aashish R. Jha,Sena Karachanak-Yankova,Rita Khusainova,Elza Khusnutdinova,Rick A. Kittles,Toomas Kivisild,William Klitz,Vaidutis Kučinskas,Alena Kushniarevich,Leila Laredj,Sergey Litvinov,Theologos Loukidis,Theologos Loukidis,Robert W. Mahley,Béla Melegh,Ene Metspalu,Julio Molina,Joanna L. Mountain,Klemetti Näkkäläjärvi,Desislava Nesheva,Thomas B. Nyambo,Ludmila P. Osipova,Jüri Parik,Fedor Platonov,Olga L. Posukh,Valentino Romano,Francisco Rothhammer,Francisco Rothhammer,Igor Rudan,Ruslan Ruizbakiev,Hovhannes Sahakyan,Hovhannes Sahakyan,Antti Sajantila,Antonio Salas,Elena B. Starikovskaya,Ayele Tarekegn,Draga Toncheva,Shahlo Turdikulova,Ingrida Uktveryte,Olga Utevska,René Vasquez,Mercedes Villena,Mikhail Voevoda,Cheryl A. Winkler,Levon Yepiskoposyan,Pierre Zalloua,Pierre Zalloua,Tatijana Zemunik,Alan Cooper,Cristian Capelli,Mark G. Thomas,Andres Ruiz-Linares,Sarah A. Tishkoff,Lalji Singh,Kumarasamy Thangaraj,Richard Villems,Richard Villems,Richard Villems,David Comas,Rem I. Sukernik,Mait Metspalu,Matthias Meyer,Evan E. Eichler,Joachim Burger,Montgomery Slatkin,Svante Pääbo,Janet Kelso,David Reich,David Reich,David Reich,Johannes Krause,Johannes Krause +136 more
TL;DR: The authors showed that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, ancient north Eurasians related to Upper Palaeolithic Siberians, who contributed to both Europeans and Near Easterners; and early European farmers, who were mainly of Near Eastern origin but also harboured west European hunters-gatherer related ancestry.
Journal ArticleDOI
Early farmers from across Europe directly descended from Neolithic Aegeans
Zuzana Hofmanová,Susanne Kreutzer,Garrett Hellenthal,Christian Sell,Yoan Diekmann,David Díez-del-Molino,Lucy van Dorp,Saioa López,Athanasios Kousathanas,Athanasios Kousathanas,Vivian Link,Vivian Link,Karola Kirsanow,Lara M. Cassidy,Rui Martiniano,Melanie Strobel,Amelie Scheu,Amelie Scheu,Kostas Kotsakis,Paul Halstead,Sevi Triantaphyllou,Nina Kyparissi-Apostolika,Dushka Urem-Kotsou,Christina Ziota,Fotini Adaktylou,Shyamalika Gopalan,Dean Bobo,Laura Winkelbach,Jens Blöcher,Martina Unterländer,Christoph Leuenberger,Çiler Çilingiroğlu,Barbara Horejs,Fokke Gerritsen,Stephen Shennan,Daniel G. Bradley,Mathias Currat,Krishna R. Veeramah,Daniel Wegmann,Daniel Wegmann,Mark G. Thomas,Christina Papageorgopoulou,Joachim Burger +42 more
TL;DR: This study demonstrates a direct genetic link between Mediterranean and Central European early farmers and those of Greece and Anatolia, extending the European Neolithic migratory chain all the way back to southwestern Asia.
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Journal ArticleDOI
Massive migration from the steppe was a source for Indo-European languages in Europe
Wolfgang Haak,Iosif Lazaridis,Nick Patterson,Nadin Rohland,Swapan Mallick,Bastien Llamas,Guido Brandt,Susanne Nordenfelt,Eadaoin Harney,Kristin Stewardson,Qiaomei Fu,Alissa Mittnik,Eszter Bánffy,Christos Economou,Michael Francken,Susanne Friederich,Rafael Garrido Pena,Fredrik Hallgren,Valery Khartanovich,Aleksandr Khokhlov,Michael Kunst,Pavel Kuznetsov,Harald Meller,Oleg Mochalov,Vayacheslav Moiseyev,Nicole Nicklisch,Sandra Pichler,Roberto Risch,Manuel Ángel Rojo Guerra,Christina Roth,Anna Szécsényi-Nagy,Joachim Wahl,Matthias Meyer,Johannes Krause,Dorcas Brown,David W. Anthony,Alan Cooper,Kurt W. Alt,David Reich +38 more
TL;DR: In this paper, the authors generated genome-wide data from 69 Europeans who lived between 8,000-3,000 years ago by enriching ancient DNA libraries for a target set of almost 400,000 polymorphisms.
Journal ArticleDOI
Ancient human genomes suggest three ancestral populations for present-day Europeans
Iosif Lazaridis,Iosif Lazaridis,Nick Patterson,Alissa Mittnik,Gabriel Renaud,Swapan Mallick,Swapan Mallick,Karola Kirsanow,Peter H. Sudmant,Joshua G. Schraiber,Joshua G. Schraiber,Sergi Castellano,Mark Lipson,Bonnie Berger,Bonnie Berger,Christos Economou,Ruth Bollongino,Qiaomei Fu,Kirsten I. Bos,Susanne Nordenfelt,Susanne Nordenfelt,Heng Li,Heng Li,Cesare de Filippo,Kay Prüfer,Susanna Sawyer,Cosimo Posth,Wolfgang Haak,Fredrik Hallgren,Elin Fornander,Nadin Rohland,Nadin Rohland,Dominique Delsate,Michael Francken,Jean-Michel Guinet,Joachim Wahl,George Ayodo,Hamza A. Babiker,Hamza A. Babiker,Graciela Bailliet,Elena Balanovska,Oleg Balanovsky,Ramiro Barrantes,Gabriel Bedoya,Haim Ben-Ami,Judit Bene,Fouad Berrada,Claudio M. Bravi,Francesca Brisighelli,George B.J. Busby,Francesco Calì,Mikhail Churnosov,David E. C. Cole,Daniel Corach,Larissa Damba,George van Driem,Stanislav Dryomov,Jean-Michel Dugoujon,Sardana A. Fedorova,Irene Gallego Romero,Marina Gubina,Michael F. Hammer,Brenna M. Henn,Tor Hervig,Ugur Hodoglugil,Aashish R. Jha,Sena Karachanak-Yankova,Rita Khusainova,Elza Khusnutdinova,Rick A. Kittles,Toomas Kivisild,William Klitz,Vaidutis Kučinskas,Alena Kushniarevich,Leila Laredj,Sergey Litvinov,Theologos Loukidis,Theologos Loukidis,Robert W. Mahley,Béla Melegh,Ene Metspalu,Julio Molina,Joanna L. Mountain,Klemetti Näkkäläjärvi,Desislava Nesheva,Thomas B. Nyambo,Ludmila P. Osipova,Jüri Parik,Fedor Platonov,Olga L. Posukh,Valentino Romano,Francisco Rothhammer,Francisco Rothhammer,Igor Rudan,Ruslan Ruizbakiev,Hovhannes Sahakyan,Hovhannes Sahakyan,Antti Sajantila,Antonio Salas,Elena B. Starikovskaya,Ayele Tarekegn,Draga Toncheva,Shahlo Turdikulova,Ingrida Uktveryte,Olga Utevska,René Vasquez,Mercedes Villena,Mikhail Voevoda,Cheryl A. Winkler,Levon Yepiskoposyan,Pierre Zalloua,Pierre Zalloua,Tatijana Zemunik,Alan Cooper,Cristian Capelli,Mark G. Thomas,Andres Ruiz-Linares,Sarah A. Tishkoff,Lalji Singh,Kumarasamy Thangaraj,Richard Villems,Richard Villems,Richard Villems,David Comas,Rem I. Sukernik,Mait Metspalu,Matthias Meyer,Evan E. Eichler,Joachim Burger,Montgomery Slatkin,Svante Pääbo,Janet Kelso,David Reich,David Reich,David Reich,Johannes Krause,Johannes Krause +136 more
TL;DR: It is shown that most present-day Europeans derive from at least three highly differentiated populations: west European hunter-gatherers, who contributed ancestry to all Europeans but not to Near Easterners; ancient north Eurasians related to Upper Palaeolithic Siberians; and early European farmers, who were mainly of Near Eastern origin but also harboured west Europeanhunter-gatherer related ancestry.
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Iosif Lazaridis,Iosif Lazaridis,Nick Patterson,Alissa Mittnik,Gabriel Renaud,Swapan Mallick,Swapan Mallick,Karola Kirsanow,Peter H. Sudmant,Joshua G. Schraiber,Joshua G. Schraiber,Sergi Castellano,Mark Lipson,Bonnie Berger,Bonnie Berger,Christos Economou,Ruth Bollongino,Qiaomei Fu,Kirsten I. Bos,Susanne Nordenfelt,Susanne Nordenfelt,Heng Li,Heng Li,Cesare de Filippo,Kay Prüfer,Susanna Sawyer,Cosimo Posth,Wolfgang Haak,Fredrik Hallgren,Elin Fornander,Nadin Rohland,Nadin Rohland,Dominique Delsate,Michael Francken,Jean-Michel Guinet,Joachim Wahl,George Ayodo,Hamza A. Babiker,Hamza A. Babiker,Graciela Bailliet,Elena Balanovska,Oleg Balanovsky,Ramiro Barrantes,Gabriel Bedoya,Haim Ben-Ami,Judit Bene,Fouad Berrada,Claudio M. Bravi,Francesca Brisighelli,George B.J. Busby,Francesco Calì,Mikhail Churnosov,David E. C. Cole,Daniel Corach,Larissa Damba,George van Driem,Stanislav Dryomov,Jean-Michel Dugoujon,Sardana A. Fedorova,Irene Gallego Romero,Marina Gubina,Michael F. Hammer,Brenna M. Henn,Tor Hervig,Ugur Hodoglugil,Aashish R. Jha,Sena Karachanak-Yankova,Rita Khusainova,Elza Khusnutdinova,Rick A. Kittles,Toomas Kivisild,William Klitz,Vaidutis Kučinskas,Alena Kushniarevich,Leila Laredj,Sergey Litvinov,Theologos Loukidis,Theologos Loukidis,Robert W. Mahley,Béla Melegh,Ene Metspalu,Julio Molina,Joanna L. Mountain,Klemetti Näkkäläjärvi,Desislava Nesheva,Thomas B. Nyambo,Ludmila P. Osipova,Jüri Parik,Fedor Platonov,Olga L. Posukh,Valentino Romano,Francisco Rothhammer,Francisco Rothhammer,Igor Rudan,Ruslan Ruizbakiev,Hovhannes Sahakyan,Hovhannes Sahakyan,Antti Sajantila,Antonio Salas,Elena B. Starikovskaya,Ayele Tarekegn,Draga Toncheva,Shahlo Turdikulova,Ingrida Uktveryte,Olga Utevska,René Vasquez,Mercedes Villena,Mikhail Voevoda,Cheryl A. Winkler,Levon Yepiskoposyan,Pierre Zalloua,Pierre Zalloua,Tatijana Zemunik,Alan Cooper,Cristian Capelli,Mark G. Thomas,Andres Ruiz-Linares,Sarah A. Tishkoff,Lalji Singh,Kumarasamy Thangaraj,Richard Villems,Richard Villems,Richard Villems,David Comas,Rem I. Sukernik,Mait Metspalu,Matthias Meyer,Evan E. Eichler,Joachim Burger,Montgomery Slatkin,Svante Pääbo,Janet Kelso,David Reich,David Reich,David Reich,Johannes Krause,Johannes Krause +136 more