Transcriptional regulatory code of a eukaryotic genome
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Cites background or methods from "Transcriptional regulatory code of ..."
...001) (Harbison et al., 2004), the presence of a perfect or near perfect Gcn4 consensus binding site (TGASTCA) in the region of −400 bp to +50 bp, and a greater than 2-fold change in steady-state mRNA levels dependent on Gcn4 when shifted to amino acid starvation medium (Natarajan et al....
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...Conserved binding sites for transcriptional regulators (Harbison et al., 2004) are depicted as colored boxes....
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...Global Map of Histone Marks We recently mapped the locations of conserved transcription-factor binding sites throughout the yeast genome (Harbison et al., 2004)....
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...These esults demonstrate that the new array and protocol odifications provide substantially higher resolution nd accuracy than our previous method using selfrinted arrays (Harbison et al., 2004; Lee et al., 2002)....
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...A positive list of 84 genes (Table S1) was selected on the basis of previous highconfidence binding data (p % 0.001) (Harbison et al., 2004), the presence of a perfect or near perfect Gcn4 consensus binding site (TGASTCA) in the region of −400 bp to +50 bp, and a greater than 2-fold change in…...
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