Transkingdom Control of Microbiota Diurnal Oscillations Promotes Metabolic Homeostasis
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...It is noteworthy that the gut microbiome is highly dynamic, exhibiting daily cyclic fluctuations which have repercussions on host metabolism and provide evidence for a crossregulation of prokaryotic and eukaryotic circadian rhythms (Thaiss et al., 2014; Zarrinpar et al., 2014)....
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"Transkingdom Control of Microbiota ..." refers methods in this paper
...We therefore performed shotgun metagenomic sequencing of fecal samples collected every 6 hr over the course of two light-dark cycles and mapped the metagenomic reads to a gut microbial gene catalog (Qin et al., 2010)....
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"Transkingdom Control of Microbiota ..." refers background in this paper
...Interestingly, Firmicutes have been associated with a higher propensity for obesity and metabolic disease in multiple human studies (Ley et al., 2006; Ridaura et al., 2013)....
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