Journal ArticleDOI
Treatment of stage I and II non-small cell lung cancer: Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines.
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TLDR
Surgical resection remains the primary and preferred approach to the treatment of stage I and II NSCLC, and mediastinal lymph node sampling at the time of curative intent surgical resection can be performed without increased morbidity.About:
This article is published in Chest.The article was published on 2013-05-01. It has received 1180 citations till now. The article focuses on the topics: Pneumonectomy & Lymphadenectomy.read more
Citations
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Journal ArticleDOI
Methods for Staging Non-small Cell Lung Cancer: Diagnosis and Management of Lung Cancer, 3rd ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines
Gerard A. Silvestri,Anne V. Gonzalez,Michael A. Jantz,Mitchell L. Margolis,Michael K. Gould,Lynn T. Tanoue,Loren J. Harris,Frank C. Detterbeck +7 more
TL;DR: It is demonstrated that PET scanning is more accurate than CT scanning, but tissue biopsy is still required to confirm PET scan findings, and evidence suggests that more complete staging improves patient outcomes.
Journal ArticleDOI
Non-small cell lung cancer: current treatment and future advances
Cecilia Zappa,Shaker A. Mousa +1 more
TL;DR: Current treatments including surgery, chemotherapy, radiotherapy, and immunotherapy are discussed as well as how biomarker testing has helped improve survival in patients with NSCLC.
Journal ArticleDOI
Overall Survival and Long-Term Safety of Nivolumab (Anti–Programmed Death 1 Antibody, BMS-936558, ONO-4538) in Patients With Previously Treated Advanced Non–Small-Cell Lung Cancer
Scott N. Gettinger,Leora Horn,Leena Gandhi,David R. Spigel,Scott J. Antonia,Naiyer A. Rizvi,John D. Powderly,Rebecca S. Heist,Richard D. Carvajal,David M. Jackman,Lecia V. Sequist,David Smith,Philip D. Leming,David P. Carbone,Mary Pinder-Schenck,Suzanne L. Topalian,F. Stephen Hodi,Jeffrey A. Sosman,Mario Sznol,David F. McDermott,Drew M. Pardoll,Vindira Sankar,Christoph Matthias Ahlers,Mark E. Salvati,Jon M. Wigginton,Matthew D. Hellmann,Georgia Kollia,Ashok Kumar Gupta,Julie R. Brahmer +28 more
TL;DR: Nivolumab monotherapy produced durable responses and encouraging survival rates in patients with heavily pretreated NSCLC, and overall survival, response durability, and long-term safety were reported.
Journal ArticleDOI
Guidelines for enhanced recovery after lung surgery: recommendations of the Enhanced Recovery After Surgery (ERAS®) Society and the European Society of Thoracic Surgeons (ESTS)
Timothy J.P. Batchelor,Neil J. Rasburn,Etienne Abdelnour-Berchtold,Alessandro Brunelli,Robert J. Cerfolio,Michel Gonzalez,Olle Ljungqvist,René Horsleben Petersen,Wanda M. Popescu,Peter Slinger,Babu Naidu +10 more
TL;DR: This review aims to present consensus recommendations for the optimal perioperative management of patients undergoing thoracic surgery (principally lung resection) using meta-analyses, randomized controlled trials, large non-randomized studies and reviews.
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Lung cancer: Biology and treatment options
TL;DR: The purpose of this review is to summarize the recent developments in lung cancer biology and its therapeutic strategies, and discuss the latest treatment advances including therapies currently under clinical investigation.
References
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Journal ArticleDOI
Hospital Volume and Surgical Mortality in the United States
John D. Birkmeyer,Andrea E. Siewers,Emily Finlayson,Therese A. Stukel,F. Lee Lucas,Ida Batista,H. Gilbert Welch,David E. Wennberg +7 more
TL;DR: Mortality decreased as volume increased for all 14 types of procedures, but the relative importance of volume varied markedly according to the type of procedure.
Journal Article
Chemotherapy in non-small cell lung cancer: A meta-analysis using updated data on individual patients from 52 randomised clinical trials
TL;DR: The results of this meta-analysis suggest that chemotherapy may have a role in treating non-small cell lung cancer, and reached conventional levels of significance when used with radical radiotherapy and with supportive care.
Journal ArticleDOI
Randomized trial of lobectomy versus limited resection for T1 N0 non-small cell lung cancer
TL;DR: Compared with lobectomy, limited pulmonary resection does not confer improved perioperative morbidity, mortality, or late postoperative pulmonary function and lobectomy still must be considered the surgical procedure of choice for patients with peripheral T1 N0 non-small cell lung cancer.
Journal ArticleDOI
Stereotactic Body Radiation Therapy for Inoperable Early Stage Lung Cancer
Robert Timmerman,Rebecca Paulus,James M. Galvin,Jeff M. Michalski,William L. Straube,Jeffrey D. Bradley,Achilles J. Fakiris,Andrea Bezjak,Gregory M.M. Videtic,David W. Johnstone,Jack F. Fowler,Elizabeth Gore,Hak Choy +12 more
TL;DR: Patients with inoperable non-small cell lung cancer who received stereotactic body radiation therapy had a survival rate of 55.8% at 3 years, high rates of local tumor control, and moderate treatment-related morbidity.
Journal ArticleDOI
Lung Adjuvant Cisplatin Evaluation: A Pooled Analysis by the LACE Collaborative Group
Jean Pierre Pignon,Hélène Tribodet,Giorgio V. Scagliotti,Jean-Yves Douillard,Frances A. Shepherd,Richard J. Stephens,Ariane Dunant,Valter Torri,Rafael Rosell,Lesley Seymour,Stephen G. Spiro,Estelle Rolland,Roldano Fossati,Delphine Aubert,Keyue Ding,David A. Waller,Thierry Le Chevalier +16 more
TL;DR: Postoperative cisplatin-based chemotherapy significantly improves survival in patients with non-small-cell lung cancer (NSCLC).