Trial Publication after Registration in ClinicalTrials.Gov: A Cross-Sectional Analysis
Citations
3,108 citations
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Cites background from "Trial Publication after Registratio..."
...Tracking the existence of clinical trials and a priori primary outcome measures provides the potential to monitor the selective publication of trials and trial results (5, 6)....
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...Concern remains that certain data, including descriptions of primary outcomes, are insufficiently detailed, but the use of these trial records already allows identification of inconsistencies between data elements reported in the registry and those reported in the final article (5, 6)....
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References
4,570 citations
"Trial Publication after Registratio..." refers background in this paper
...Similarly unpublished clinical trials of rosiglitazone [3] identified from a company-maintained website and of erythropoiesis-stimulating agents [4] and antidepressants [5] found among data submitted to the FDA revealed important efficacy and safety information to be missing from the medical literature....
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...Other evidence concerning selective publication is anecdotal, such as the absence of 6 mo of trial data from a key publication describing the efficacy of celecoxib [25,26], the delay of publication for two early trials of rofecoxib until after the medication was withdrawn from the market [27–29], and the aforementioned studies of rosiglitazone [3], erythropoiesis-stimulating agents [4], and antidepressants [5]....
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"Trial Publication after Registratio..." refers background in this paper
...Many studies have attempted to evaluate the extent of selective publication in the biomedical literature and found similarly low rates of publication [5,12–24], although none have used, to our knowledge, as large and as broadly representative a registry as ClinicalTrials....
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2,176 citations
"Trial Publication after Registratio..." refers background or result in this paper
...Similarly unpublished clinical trials of rosiglitazone [3] identified from a company-maintained website and of erythropoiesis-stimulating agents [4] and antidepressants [5] found among data submitted to the FDA revealed important efficacy and safety information to be missing from the medical literature....
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...Given the documented presence of outcome reporting bias among trials studied in other settings [5,12,13], the potential impact of ClinicalTrials....
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...Other evidence concerning selective publication is anecdotal, such as the absence of 6 mo of trial data from a key publication describing the efficacy of celecoxib [25,26], the delay of publication for two early trials of rofecoxib until after the medication was withdrawn from the market [27–29], and the aforementioned studies of rosiglitazone [3], erythropoiesis-stimulating agents [4], and antidepressants [5]....
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1,917 citations
"Trial Publication after Registratio..." refers result in this paper
...However, we also found significantly different publication rates among study types and primary sponsors, consistent with prior research [11]....
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