Journal ArticleDOI
Two amides from Piper brachystachyum
Avijit Banerji,Chittaranjan Das +1 more
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TLDR
Two new unsaturated amides were isolated from the total above-ground parts of Piper brachystachyum and were shown to be N-isobutyl-15 (3′,4′-methylenedioxyphenyl) 2E,4E-pentadecadienamide from spectroscopic and chemical investigations.About:
This article is published in Phytochemistry.The article was published on 1989-01-01. It has received 25 citations till now. The article focuses on the topics: Piperaceae & Piper.read more
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Journal ArticleDOI
Phytochemistry of the genus Piper
Virinder S. Parmar,Subhash C. Jain,Kirpal S. Bisht,Rajni Jain,Poonam Taneja,Amitabh Jha,O. D. Tyagi,Ashok K. Prasad,Jesper Wengel,Carl Erik Olsen,Per M. Boll,Per M. Boll +11 more
TL;DR: The secondary metabolites isolated from Piper species for the period 1907 to June 1996 have been reviewed in this paper, where nearly six hundred chemical constituents belonging to different classes of bioactive compounds are listed together with their source(s) and references.
Journal ArticleDOI
Chemical constituents and bioactivity of Piper sarmentosum.
Thitima Rukachaisirikul,Puttan Siriwattanakit,Kanchanawadee Sukcharoenphol,Chanika Wongvein,Phongpan Ruttanaweang,Phaopong Wongwattanavuch,Apichart Suksamrarn +6 more
TL;DR: The results showed that compounds 4 and 6 exhibited both activities while compounds 1, 2, 5, 8 and 11 showed only antituberculosis activity, the first report of the antituber tuberculosis and antiplasmodial activities for these compounds.
Journal ArticleDOI
Constituents of Chinese Piper species and their inhibitory activity on prostaglandin and leukotriene biosynthesis in vitro.
TL;DR: The n-hexane extracts of 19 Piper species, predominantly from China, were screened for their 5-lipoxygenase (5-LOX) and cyclo oxygengenase-1 (COX-1) inhibitory potential and showed considerable inhibitory activity against at least one of these two key enzymes of the arachidonic acid metabolism.
Journal ArticleDOI
Protective effects of amide constituents from the fruit of Piper chaba on D-galactosamine/TNF-α-induced cell death in mouse hepatocytes
Hisashi Matsuda,Kiyofumi Ninomiya,Kiyofumi Ninomiya,Toshio Morikawa,Toshio Morikawa,Daisuke Yasuda,Itadaki Yamaguchi,Masayuki Yoshikawa +7 more
TL;DR: A principal amide constituent, piperine, dose-dependently inhibited increase in serum GPT and GOT levels at doses of 2.5-10 mg/kg (p.o.) in D-GalN/LPS-treated mice, and this inhibitory effect was suggested to depend on the reduced sensitivity of hepatocytes to TNF-alpha.
Journal ArticleDOI
Hepatoprotective amide constituents from the fruit of Piper chaba: Structural requirements, mode of action, and new amides.
Hisashi Matsuda,Kiyofumi Ninomiya,Kiyofumi Ninomiya,Toshio Morikawa,Toshio Morikawa,Daisuke Yasuda,Itadaki Yamaguchi,Masayuki Yoshikawa +7 more
TL;DR: The 80% aqueous acetone extract from the fruit of Piper chaba (Piperaceae) was found to have hepatoprotective effects on D-galactosamine (D-GalN)/lipopolysaccharide-induced liver injury in mice, and the following structural requirements were suggested.
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Structural and synthetic studies on the retrofractamides—amide constituents of Piper retrofractum
Avijit Banerji,Debabrata Bandyopadhyay,Manjusha Sarkar,Arup K. Siddhanta,Sudhir C. Pal,Somnath Ghosh,Koshy Abraham,James N. Shoolery +7 more
TL;DR: In this article, two unsaturated amides, retrofractamides A and C, were isolated from the total aboveground parts of Piper retroractum and were shown to be N -isobutyl-9(3′,4′-methylenedioxyphenyl)2 E,4 E,8 E -nonatrienamide from spectroscopic and chemical investigations.
Journal ArticleDOI
Total synthesis of sylvamide, A Piper alkamide
Avijit Banerji,Sudhir C. Pal +1 more
TL;DR: The structure of N-isobutyl-4,5-dihydroxy-2(E)-decenamide for sylvamide is confirmed by its total synthesis as mentioned in this paper.
Journal ArticleDOI
A new alkamide from Piper sylvaticum
Avijit Banerji,Sudhir C. Pal +1 more
TL;DR: Sylvamide, a new amide derivative, has been isolated from the petrol extract of the seeds of Piper sylvaticum (Roxb) from spectral and chemical properties as discussed by the authors.