Journal ArticleDOI
Two formulas for computation of the area under the curve represent measures of total hormone concentration versus time-dependent change
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It is shown that depending on which formula is used, different associations with other variables may emerge, and it is recommended to employ both formulas when analyzing data sets with repeated measures.About:
This article is published in Psychoneuroendocrinology.The article was published on 2003-10-01. It has received 3185 citations till now.read more
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The Netherlands Study of Depression and Anxiety (NESDA): rationale, objectives and methods.
Brenda W.J.H. Penninx,Aartjan T.F. Beekman,Jan Smit,Frans G. Zitman,Willem A. Nolen,Philip Spinhoven,Pim Cuijpers,de Peter Jong,H.W.J. van Marwijk,Willem J J Assendelft,van der Klaas Meer,Peter F. M. Verhaak,Michel Wensing,R. de Graaf,Witte J.G. Hoogendijk,Johan Ormel,R. van Dyck +16 more
TL;DR: The Netherlands Study of Depression and Anxiety is a multi‐site naturalistic cohort study to describe the long‐term course and consequences of depressive and anxiety disorders and to integrate biological and psychosocial research paradigms within an epidemiological approach.
Journal ArticleDOI
The awakening cortisol response: Methodological issues and significance
TL;DR: A review explores reasons for discrepancies in normative data including confounding factors such as gender, age, awakening time, light and participant adherence that suggest the awakening cortisol response is under a distinct regulatory influence different from the rest of the diurnal cortisol secretory cycle.
Journal ArticleDOI
Assessing salivary cortisol in large-scale, epidemiological research.
Emma K. Adam,Meena Kumari +1 more
TL;DR: Examples of choices made, response rates obtained, and examples of results obtained from existing epidemiological cortisol studies are offered, as are suggestions for the modeling and interpretation of salivary cortisol data obtained in large-scale epidemiological research.
Journal ArticleDOI
Assessment of the cortisol awakening response: Expert consensus guidelines.
Tobias Stalder,Clemens Kirschbaum,Brigitte M. Kudielka,Emma K. Adam,Jens C. Pruessner,Stefan Wüst,Samantha Dockray,Nina Smyth,Phil Evans,Dirk H. Hellhammer,Robert Miller,Mark Wetherell,Sonia J. Lupien,Angela Clow +13 more
TL;DR: Consensus guidelines are presented on central aspects of CAR assessment, including objective control of sampling accuracy/adherence, participant instructions, covariate accounting, sampling protocols, quantification strategies as well as reporting and interpreting of CAR data.
Journal ArticleDOI
Major depressive disorder and hypothalamic-pituitary-adrenal axis activity: results from a large cohort study.
Sophie A. Vreeburg,Witte J.G. Hoogendijk,Johannes van Pelt,Roel H. DeRijk,Jolanda C. M. Verhagen,Richard van Dyck,Johannes H. Smit,Frans G. Zitman,Brenda W.J.H. Penninx +8 more
TL;DR: This large cohort study shows significant, although modest, associations between major depressive disorder and specific hypothalamic-pituitary-adrenal axis indicators and a higher cortisol awakening response was observed among both subjects with current MDD and subjects with remitted MDD, indicative of an increased biological vulnerability for depression.
References
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The effect of finasteride in men with benign prostatic hyperplasia. The Finasteride Study Group.
Glenn J. Gormley,Elizabeth Stoner,Reginald C. Bruskewitz,Julianne Imperato-McGinley,Patrick C. Walsh,John D. McConnell,Gerald L. Andriole,Jack Geller,Bruce Bracken,J S Tenover +9 more
TL;DR: The effect of finasteride (1 mg and 5 mg) on prostate hyperplasia was evaluated in 895 men with prostate cancer in a double-blind study as discussed by the authors.
Journal ArticleDOI
Burnout, perceived stress, and cortisol responses to awakening.
TL;DR: Sixty-six teachers from local public schools (42 womenand 24 men, mean age 42 6 5 years) were asked to sample saliva for cortisol analysis on 3 consecutive days as discussed by the authors.
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Increased free cortisol secretion after awakening in chronically stressed individuals due to work overload
TL;DR: It is concluded that a repeated measurement of free cortisol in response to awakening should be considered a possible biological correlate of chronic stress.
Journal ArticleDOI
Trierer Inventar zur Erfassung von chronischem Streß (TICS): Skalenkonstruktion, teststatistische Überprüfung und Validierung der Skala Arbeitsüberlastung
Peter Schulz,Wolff Schlotz +1 more
TL;DR: Zusammenfassung as mentioned in this paper is a method for stresforschung, wonach chronischer Stres und nicht akute Belastungen mit klinisch relevanten Beeintrachtigungen der Gesundheit in Zusammanhang steht.
Journal ArticleDOI
Increasing correlations between personality traits and cortisol stress responses obtained by data aggregation
Jens C. Pruessner,Jens Gaab,Dirk H. Hellhammer,Doris Lintz,Nicole C. Schommer,Clemens Kirschbaum +5 more
TL;DR: Preliminary evidence is provided for a relationship between questionnaire scales aiming at assessing personality traits and cortisol stress responses uncovered by repeated stress exposure and data aggregation.