Ultracytochemical localizations of alkaline phosphatase and acid phosphatase activities in the human term placenta
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This article is published in Acta Histochemica Et Cytochemica.The article was published on 1987-01-01 and is currently open access. It has received 23 citations till now. The article focuses on the topics: Acid phosphatase & Alkaline phosphatase.read more
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Book ChapterDOI
Basic Structure of the Villous Trees
M. Castellucci,Peter Kaufmann +1 more
TL;DR: In the placental villi, nearly the entire maternofetal and fetomaternal exchange takes place and there is only a limited contribution to this exchange by the extraplacental membranes.
Journal ArticleDOI
Insulin binding to trophoblast plasma membranes and placental glycogen content in well-controlled gestational diabetic women treated with diet or insulin, in well-controlled overt diabetic patients and in healthy control subjects
TL;DR: It is concluded that trophoblast plasma membranes from gestational diabetic women treated with diet alone express less and those from women treating with insulin express more insulin receptors than those from a healthy control group in vitro.
Journal ArticleDOI
Ultrastructural Changes and Immunocytochemical Analysis of Human Placental Trophoblast During Short-term Culture
Christopher M.R. Bax,Timothy A. Ryder,Margaret A. Mobberley,A. Stanley Tyms,Taylor Debra Lynn,David L. Bloxam +5 more
TL;DR: The results support the idea that the isolated cells are cytotrophic cells and that these differentiate during this time into cells with characteristics of villous syncytiotrophoblast.
Journal ArticleDOI
Two-sided culture of human placental trophoblast. Morphology, immunocytochemistry and permeability properties.
Bridget E. Bullen,David L. Bloxam,Timothy A. Ryder,Margaret A. Mobberley,Christopher M.R. Bax +4 more
TL;DR: A preliminary investigation of the permeability properties of the preparation showed that the trophoblast cell layer was rate-limiting to transtrophoblast transfer, but that possible effects of the supporting membrane should be considered.
Journal ArticleDOI
Ultracytochemical localizations of adenylate cyclase, guanylate cyclase and cyclic 3',5'-nucleotide phosphodiesterase activity on the trophoblast in the human placenta. Direct histochemical evidence.
TL;DR: It is suggested that the syncytiotrophoblast plays an important role in the cyclic nucleotide metabolism in the human term placenta and that there might be significant functional differences between its basal plasma membrane and its microvillous membrane.
References
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Journal ArticleDOI
Ultrastructural localization of several phosphatases with cerium.
J M Robinson,Morris J. Karnovsky +1 more
TL;DR: Cerium appears to be a better capture agent for inorganic phosphate than lead in that reaction product is usually more uniform and more consistently reproducible when cerium is used.
Journal ArticleDOI
The new lead citrate method for the ultracytochemical demonstration of activity of non-specific alkaline phosphatase (orthophosphoric monoester phosphohydrolase).
TL;DR: The new method, utilizing “lead citrate” as capture reagent, for the ultracytochemical demonstration of non-specific alkaline phosphatase activity at high alkaline ranges of pH was introduced.
Journal ArticleDOI
The cytochemical application of new potent inhibitors of alkaline phosphatases
TL;DR: The inhibitory properties of levamisole and its analogue R 8231 on alkaline phosphatases of various rat tissues were investigated cytochemically and found to be substrate-independent and reversible as for other known uncompetetive inhibitors.