Journal ArticleDOI
Ultrafast Synthesis of Ultrasmall Poly(Vinylpyrrolidone)-Protected Bismuth Nanodots as a Multifunctional Theranostic Agent for In Vivo Dual-Modal CT/Photothermal-Imaging-Guided Photothermal Therapy
Pengpeng Lei,Ran An,Peng Zhang,Shuang Yao,Shuyan Song,Lile Dong,Lile Dong,Xia Xu,Kaimin Du,Kaimin Du,Jing Feng,Hongjie Zhang +11 more
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TLDR
Positive results reveal that PVP‐Bi nanodots produced through the ultrafacile method are promising single‐“element” nanotheranostic platform for dual‐modal CT/photothermal‐imaging‐guided PTT.Abstract:
To elaborately fabricate real-time monitoring and therapeutic function into a biocompatible nanoplatform is a promising route in the cancer therapy field. However, the package of diagnosis and treatment into a single-“element” nanoparticle remains challenge. Herein, ultrasmall poly(vinylpyrrolidone)-protected bismuth nanodots (PVP-Bi nanodots) are successfully synthesized through an ultrafacile strategy (1 min only under ambient conditions). The nanodots are easy to synthesize in both laboratory and large scale using low-cost bismuth ingredients. PVP-Bi nanodots with ultrasmall size show good biocompatibility. Due to the high X-ray attenuation ability of Bi element, PVP-Bi nanodots have prominent performance on X-ray computed tomography (CT) imaging. Moreover, PVP-Bi nanodots exhibit a high photothermal conversion efficiency (η = 30%) because of the strong near-infrared absorbance, which can serve as nanotheranostic agent for photothermal imaging and cancer therapy. The subsequent PVP-Bi-nanodot-mediated photothermal therapy (PTT) result shows highly efficient ablation of cancer cells both in vitro and in vivo. PVP-Bi nanodots can be almost completely excreted from mice after 7 d. Blood biochemistry and histology analysis suggests that PVP-Bi nanodots have negligible toxicity. All the positive results reveal that PVP-Bi nanodots produced through the ultrafacile method are promising single-“element” nanotheranostic platform for dual-modal CT/photothermal-imaging-guided PTT.read more
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Journal ArticleDOI
Emerging two-dimensional monoelemental materials (Xenes) for biomedical applications
Wei Tao,Na Kong,Xiaoyuan Ji,Yupeng Zhang,Amit Sharma,Jiang Ouyang,Baowen Qi,Junqing Wang,Ni Xie,Chulhun Kang,Han Zhang,Omid C. Farokhzad,Jong Seung Kim +12 more
TL;DR: This tutorial review summarizes their general properties including the classification of Xenes according to their bulk properties, as well as the synthetic and modification methods of Xene.
Journal ArticleDOI
Metal Ion/Tannic Acid Assembly as a Versatile Photothermal Platform in Engineering Multimodal Nanotheranostics for Advanced Applications.
Tao Liu,Ming-Kang Zhang,Wen-Long Liu,Xuan Zeng,Xianlin Song,Xiaoquan Yang,Xian-Zheng Zhang,Jun Feng +7 more
TL;DR: PNV@FeIIITA can be simultaneously equipped with functionalities, including T2-MRI imaging by additionally doping MnII and NIR fluorescence imaging by encapsulating a hydrophilic NIR fluoroprobe, and MITA demonstrates unparalleled superiority as a photothermal platform in engineering multimodal theranostics for advanced applications.
Journal ArticleDOI
The versatile biomedical applications of bismuth-based nanoparticles and composites: therapeutic, diagnostic, biosensing, and regenerative properties
Mohammad-Ali Shahbazi,Mohammad-Ali Shahbazi,Leila Faghfouri,Mónica P. A. Ferreira,Patrícia Figueiredo,Hajar Maleki,Farshid Sefat,Jouni Hirvonen,Hélder A. Santos +8 more
TL;DR: This review emphasizes the synthesis and state-of-the-art progress related to the biomedical applications of BiNPs with different structures, sizes, and compositions.
Journal ArticleDOI
Ultrasmall Bismuth Quantum Dots: Facile Liquid-Phase Exfoliation, Characterization, and Application in High-Performance UV–Vis Photodetector
Chenyang Xing,Weichun Huang,Zhongjian Xie,Jinlai Zhao,Dingtao Ma,Taojian Fan,Weiyuan Liang,Yanqi Ge,Biqin Dong,Jianqing Li,Han Zhang +10 more
TL;DR: In this paper, a 2D monoelemental bismuth crystal with an average diameter (thickness) of 4.9 ± 1.0 nm (2.6 ± 0.7 nm) was fabricated through facile liquid-phase exfoliation (LPE) method, and the corresponding photoresponse was evaluated using photoelectrochemical (PEC) measurements.
Journal ArticleDOI
0D Bi nanodots/2D Bi3NbO7 nanosheets heterojunctions for efficient visible light photocatalytic degradation of antibiotics: Enhanced molecular oxygen activation and mechanism insight
TL;DR: In this paper, a 0D Bi nanodots/2D Bi3NbO7 nanosheets heterostructured composite with enhanced molecular oxygen activation under visible light irradiation, which was synthesized by a two-step wet chemical method.
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