Uncaria tomentosa extract: evaluation of effects on the in vitro and in vivo labeling of blood constituents with technetium-99m
Silvana Ramos Farias Moreno,Silvana Ramos Farias Moreno,Jorge José de Carvalho,Ana Lucia Rosa Nascimento,Beni Olej,Emely Kazan Rocha,Adriano Arnobio,Mario Bernardo-Filho,Luiz Querino de Araújo Caldas,Hayden Honeycut +9 more
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TLDR
The analysis of the results of the in vivo and in vitro study indicates that there is no significant alteration on the uptake of Tc-99m by the blood constituents, but it significantly decrease the labeling of blood constituents by in vitro methods.Abstract:
The influence (in vivo and in vitro) of an Uncaria tomentosa extract (Cats claw) on the labeling of red blood cells (RBCs) and plasma and cellular proteins with technetium-99m (Tc-99m) was evaluated. For the in vivo treatment, animals were treated with Cats claw. For the in vitro treatment, heparinized blood was incubated with Cats claw before the addition of stannous chloride (SnCl2) and Tc-99m. Samples of plasma (P) and RBCs were separated and also precipitated with trichloroacetic acid. The soluble and insoluble fractions of P and RBCs were isolated. The analysis of the results of the in vivo study, indicates that there is no significant alteration on the uptake of Tc-99m by the blood constituents, but it significantly decrease (p<0.05) the labeling of blood constituents by in vitro methods. These effects could be due to chelation of stannous and /or pertechnetate ions and blockage of the Tc-99m bindings sites.read more
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Effect of a peel passion fruit flour (Passiflora edulis f. flavicarpa) extract on the labeling of blood constituents with technetium-99m and on the morphology of red blood cells
Bernardo Machado Rebello,Bernardo Machado Rebello,Silvana Ramos Farias Moreno,Silvana Ramos Farias Moreno,Camila Godinho Ribeiro,Camila Godinho Ribeiro,Rosane de Figueiredo Neves,Rosane de Figueiredo Neves,Adenilson de Souza da Fonseca,Luis Querino de Araújo Caldas,Mario Bernardo-Filho,Mario Bernardo-Filho,Aldo Cunha Medeiros +12 more
TL;DR: Substances present in P. flavicarpa extract could affect the labeling of blood constituents with 99mTc acting in specific targets as membrane of red blood cells.
Journal ArticleDOI
Ginkgo biloba extract alters the binding of the sodium [123I] iodide (Na123I) on blood constituents.
L.C.M. Aleixo .,S.R.F. Moreno,R. S. Freitas,Helio F.N. Thomaz,Sebastião David Santos-Filho,Mario Bernardo-Filho +5 more
TL;DR: In vitro effect of an aqueous extract of Ginkgo biloba on the distribution in blood cells and plasma and on the binding of Na(123)I to the blood constituents using precipitation with trichloroacetic acid is evaluated.
Dissertation
Segurança e eficácia da tibolona na transição menopausal: um ensaio clínico randomizado, duplo-cego e controlado com placebo
TL;DR: It can be suggested that the effects presented by this extract could be a result of some substances contained in this extract that could alter the binding of 99mTc to plasma proteins, the morphology of RBC and the biodistribution of the radiobiocomplex sodium perthecnetate.
Journal Article
Antioxidant Activity of Ethanolic and Aqueous Extracts of Leaves of Plumeria Rubra(Linn.)
TL;DR: The present study was aimed at evaluating the free radical scavenging activity of ethanolic and aqueous leaves extract of Plumeria rubra (linn) to protect human body from free radical.
References
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Immunomodulating and antiviral activities of the imidazoquinoline S-28463
Mark A. Tomai,Sheila J. Gibson,Linda M. Imbertson,Richard L. Miller,Paula E. Myhre,Michael J. Reiter,Tamara L. Wagner,Charmille B. Tamulinas,Joseph M. Beaurline,John F. Gerster,Vicki L. Horton +10 more
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Journal ArticleDOI
Antioxidant activity of ethanolic and aqueous extracts of Uncaria tomentosa (Willd.) DC
TL;DR: High antioxidant capacity of the studied materials in comparison to the other extracts of fruits, vegetables, cereals and medicinal plants might suggest higher medical suitability of alcoholic extracts, but the highly elevated level of tannins in alcoholic extracts may cause undesirable gastric effects.
Book
Evidence-Based Herbal Medicine
Michael Rotblatt,Irwin Ziment +1 more
TL;DR: Evidence-based herbal medicine, Evidence- based herbal medicine , کتابخانه دیجیتالی علوم پزشکی و شهید بهشتی.
Journal ArticleDOI
Drug interactions with radiopharmaceuticals.
Stuart Hesslewood,Emmeline Leung +1 more
TL;DR: Considerable information on documented drug and radiopharmaceutical interactions has been assembled in a tabular form to provide a rapid reference for nuclear medicine staff to look for such interactions.