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Upper-Body Obesity, Glucose Intolerance, Hypertriglyceridemia, and Hypertension
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TLDR
Evidence is examined that upper-body obesity, as usually induced by caloric excess in the presence of androgens, mediates problems with hypertension, diabetes, and hypertriglyceridemia by way of hyperinsulinemia.Abstract:
The contribution of obesity to cardiovascular risk has not been adequately appreciated because of a failure to recognize the involvement of upper-body predominance of body weight with hypertension, diabetes, and hypertriglyceridemia even in the absence of significant overall obesity. This article examines the evidence that upper-body obesity, as usually induced by caloric excess in the presence of androgens, mediates these problems by way of hyperinsulinemia. Because of these interrelationships, there is a need to identify and prevent upper-body obesity or, failing that, to provide therapies that will control the associated problems without aggravating hyperinsulinemia.read more
Citations
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