Use and misuse of the gene ontology annotations.
Citations
13,102 citations
Cites background from "Use and misuse of the gene ontology..."
...Thus, it is recommended that the user test multiple tools, which even offer similar analytic capability, in order to obtain the most satisfactory results (75)....
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...It is not uncommon for users to try multiple tools with similar analytic capability for the same dataset in order to obtain maximum satisfactory analytic results (75)....
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1,490 citations
Cites background from "Use and misuse of the gene ontology..."
...Relatively more comprehensive and accurate versions are being produced based on the evidence codes and/or comparative genomics to reduce the substantial number of false positives (20)....
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1,357 citations
Cites background from "Use and misuse of the gene ontology..."
...Annotations inferred from indirect evidence are considered to be of lower quality than those derived from direct experimental evidence, although this opinion has not been shown robustly [54]....
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...These annotations are the only ones in GO that are not curated manually [54]....
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958 citations
856 citations
Cites background from "Use and misuse of the gene ontology..."
...Although GO-based analysis has been informative, there can be significant issues with its use (Rhee et al., 2008), particularly because there are differences in the quality of functional annotation for different genomes....
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References
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"Use and misuse of the gene ontology..." refers background in this paper
...com/">ISI Web of Knowledge ) for annotating newly sequenced genome...
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4,064 citations
"Use and misuse of the gene ontology..." refers background in this paper
...This is a typical way of providing an overview of the broad biology encoded by a genom...
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