Journal ArticleDOI
Using melt-electrowritten microfibres for tailoring scaffold mechanics of 3D bioprinted chondrocyte-laden constructs
Maureen T. Ross,David Kilian,Anja Lode,Jiongyu Ren,Mark C. Allenby,Michael Gelinsky,Maria A. Woodruff +6 more
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TLDR
The potential of algMC to be a bioink for MEW fibre-reinforced 3D printed constructs that have tailorable mechanical properties and support long-term culture of bioprinted human chondrocytes is shown.About:
This article is published in Bioprinting.The article was published on 2021-08-01. It has received 7 citations till now. The article focuses on the topics: Chondrocyte.read more
Citations
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The return of a forgotten polymer : Polycaprolactone in the 21st century
TL;DR: Polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices for up to 3-4 years as discussed by the authors.
Journal ArticleDOI
3D printing of bio-instructive materials: Toward directing the cell
TL;DR: In this paper , extrusion-based 3D printing methods (EBP) are evaluated in their ability to direct cell alignment, proliferation, differentiation, specific ECM production, and tissue maturation.
Journal ArticleDOI
Alginate based hydrogel inks for 3D bioprinting of engineered orthopedic tissues.
Sumit Murab,Aastha Gupta,Małgorzata K. Włodarczyk-Biegun,Anuj Kumar,Patrick van Rijn,Patrick W. Whitlock,Sung Soo Han,Garima Agrawal +7 more
TL;DR: In this paper , the importance of alginate-based hydrogel inks for fabricating 3D printed scaffolds for bone and cartilage regeneration is highlighted. But, the challenges and research directions relevant for future clinical translation are discussed.
Journal ArticleDOI
Algal polysaccharides for 3D printing: A review
TL;DR: A comprehensive review of available algal biomaterials, their properties, and emerging applications in 3D printing techniques is presented in this paper , where the future prospects, opportunities, and challenges for using algal polymers in the 3D printer market for a sustainable economy are discussed.
Tailoring hydrogel surface properties to modulate cellular response to shear loading
Christoph Meinert,Karsten Schrobback,Peter A. Levett,Cameron Lutton,Robert L. Sah,Travis J. Klein +5 more
TL;DR: In this paper, the effect of variations in surface friction on the biological response of human articular chondrocytes to shear loading was investigated, showing that the surface friction of tissue-engineered cartilage may act as a potent regulator of cellular homeostasis by governing the magnitude of shear deformation.
References
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Journal ArticleDOI
In situ immune response and mechanisms of cell damage in central nervous system of fatal cases microcephaly by Zika virus
Raimunda do Socorro da Silva Azevedo,Jorge Rodrigues de Sousa,Marialva Tereza Ferreira de Araújo,Arnaldo Jorge Martins Filho,Bianca Nascimento de Alcantara,Fernanda Montenegro de Carvalho Araújo,Maria G. L. Queiroz,Ana Cecília Ribeiro Cruz,Beatriz H. Baldez Vasconcelos,Jannifer Oliveira Chiang,Lívia Carício Martins,Livia Medeiros Neves Casseb,Eliana Vieira Pinto da Silva,Valéria Lima Carvalho,Barbara Cristina Baldez Vasconcelos,Sueli Rodrigues,Consuelo Silva de Oliveira,Juarez Antônio Simões Quaresma,Pedro Fernando da Costa Vasconcelos +18 more
TL;DR: The in situ immune response profile and mechanisms of neuronal cell damage in fatal Zika microcephaly cases were investigated and changes found were mainly calcification, necrosis, neuronophagy, gliosis, microglial nodules, and inflammatory infiltration of mononuclear cells.
Journal ArticleDOI
The return of a forgotten polymer—Polycaprolactone in the 21st century
TL;DR: Polycaprolactone (PCL) was used in the biomaterials field and a number of drug-delivery devices for up to 3-4 years.
Journal ArticleDOI
A 3D bioprinting system to produce human-scale tissue constructs with structural integrity
TL;DR: An integrated tissue–organ printer (ITOP) that can fabricate stable, human-scale tissue constructs of any shape is presented and the incorporation of microchannels into the tissue constructs facilitates diffusion of nutrients to printed cells, thereby overcoming the diffusion limit of 100–200 μm for cell survival in engineered tissues.
Journal ArticleDOI
25th Anniversary Article: Engineering Hydrogels for Biofabrication
Jos Malda,Jos Malda,Jetze Visser,Ferry P.W. Melchels,Ferry P.W. Melchels,Tomasz Jungst,Wim E. Hennink,Wouter J.A. Dhert,Jürgen Groll,Dietmar W. Hutmacher,Dietmar W. Hutmacher +10 more
TL;DR: This review focuses on the deposition process, the parameters and demands of hydrogels in biofabrication, with special attention to robotic dispensing as an approach that generates constructs of clinically relevant dimensions.
Journal ArticleDOI
Correction: Corrigendum: Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
John Bowes,Ashley Budu-Aggrey,Ulrike Hüffmeier,Steffen Uebe,Kathryn J. A. Steel,Harry L. Hébert,Chris Wallace,Jonathon Massey,Ian N. Bruce,James Bluett,Marie Feletar,Ann W. Morgan,Helena Marzo-Ortega,Gary Donohoe,Derek W. Morris,Philip S. Helliwell,Anthony W. Ryan,David Kane,Richard B. Warren,Eleanor Korendowych,Gerd-Marie Alenius,Emiliano Giardina,Jonathan Packham,Ross McManus,Oliver FitzGerald,Neil McHugh,Matthew A. Brown,Pauline Ho,Frank Behrens,Harald Burkhardt,André Reis,Anne Barton +31 more
TL;DR: This work presents a novel and scalable approach to genome-based approaches that combines cell reprograming, nanofiltration, and ‘spatially aggregating’ techniques that allow for real-time assessment of the impact of environmental factors on gene expression and disease progression.
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