Vaccine delivery using nanoparticles
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Cites background from "Vaccine delivery using nanoparticle..."
...This allows obtaining vaccines against the antigens that are targets of strong natural nonspecific cellular immunity [99]....
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Cites background from "Vaccine delivery using nanoparticle..."
...Strength and mechanisms of immunostimulation induced by nanocarrier vaccines depend on various factors, such as chemical composition, particle size and homogeneity, charge, nature and location of antigens and/or adjuvants within the carrier and, last but not least, the site of administration (see Figure 2) [Watson et al. 2012; Brito et al. 2013; Gregory et al. 2013; Smith et al. 2013; Zaman et al. 2013]....
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383 citations
Cites background from "Vaccine delivery using nanoparticle..."
...By using PNPs to carry antigens, the uptake effectiveness into dendritic cells is considerably amplified compared with the free antigen (Gregory et al., 2013)....
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References
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"Vaccine delivery using nanoparticle..." refers background in this paper
...The smaller particles, formed from using a strong reducing agent, can then be grown to form larger particles with a desired aspect ratio using ceyltrimethlammonium bromide and silver acetate (Turkevich et al., 1951; Bhumkar et al., 2007a; Zhou et al., 2008; Chen et al., 2010)....
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4,383 citations
"Vaccine delivery using nanoparticle..." refers background in this paper
...The results showed that the optimal size for uptake was 50 nm and uptake increased significantly for the first 2 h before plateauing at between 4 and 7 h post-exposure (Chithrani et al., 2006)....
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3,284 citations
"Vaccine delivery using nanoparticle..." refers background in this paper
...One of the greatest obstacles with liposome delivery systems is their instability (Soppimath et al., 2001; Hans and Lowman, 2002)....
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2,613 citations