Vascular comorbidities worsen prognosis of patients with heart failure hospitalised with COVID-19.
Jacob Mok,Juan Carlos Malpartida,Kimberly O’Dell,Joshua Davis,Cuilan Gao,Harish Manyam,Harish Manyam +6 more
- Vol. 8, Iss: 1
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TLDR
A case-control study was conducted of patients with prior diagnosis of heart failure hospitalised with COVID-19 at an academic tertiary care center from 1 January 2020 to 28 February 2021.Abstract:
BACKGROUND: Prior diagnosis of heart failure (HF) is associated with increased length of hospital stay (LOS) and mortality from COVID-19. Associations between substance use, venous thromboembolism (VTE) or peripheral arterial disease (PAD) and its effects on LOS or mortality in patients with HF hospitalised with COVID-19 remain unknown. OBJECTIVE: This study identified risk factors associated with poor in-hospital outcomes among patients with HF hospitalised with COVID-19. METHODS: Case-control study was conducted of patients with prior diagnosis of HF hospitalised with COVID-19 at an academic tertiary care centre from 1 January 2020 to 28 February 2021. Patients with HF hospitalised with COVID-19 with risk factors were compared with those without risk factors for clinical characteristics, LOS and mortality. Multivariate regression was conducted to identify multiple predictors of increased LOS and in-hospital mortality in patients with HF hospitalised with COVID-19. RESULTS: Total of 211 patients with HF were hospitalised with COVID-19. Women had longer LOS than men (9 days vs 7 days; p<0.001). Compared with patients without PAD or ischaemic stroke, patients with PAD or ischaemic stroke had longer LOS (7 days vs 9 days; p=0.012 and 7 days vs 11 days, p<0.001, respectively). Older patients (aged 65 and above) had increased in-hospital mortality compared with younger patients (adjusted OR: 1.04; 95% CI 1.00 to 1.07; p=0.036). Prior diagnosis of VTE increased mortality more than threefold in patients with HF hospitalised with COVID-19 (adjusted OR: 3.33; 95% CI 1.29 to 8.43; p=0.011). CONCLUSION: Vascular diseases increase LOS and mortality in patients with HF hospitalised with COVID-19.read more
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Association of chronic heart failure with mortality in old intensive care patients suffering from Covid‐19
Raphael Romano Bruno,Bernhard Wernly,Georg Wolff,Jesper Fjølner,Antonio Artigas,Bernardo Bollen Pinto,Joerg C. Schefold,Detlef Kindgen-Milles,Philipp Heinrich Baldia,Malte Kelm,Michael Beil,Sigal Sviri,P. V. Van Heerden,Wojciech Szczeklik,Arzu Topeli,Muhammed Elhadi,Michael Joannidis,Sandra Oeyen,Eumorfia Kondili,Brian Marsh,Finn H. Andersen,Rui Moreno,Susannah Leaver,Ariane Boumendil,Dylan W. de Lange,Bertrand Guidet,Hans Flaatten,Christian Jung +27 more
TL;DR: This prospective international multicentre study investigates the role of pre‐existing CHF on clinical outcomes of critically ill old (≥70 years) intensive care patients with COVID‐19.
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TL;DR: In this paper, a study aimed to determine whether disease severity varied according to whether coronavirus disease 2019 (COVID-19) patients had multiple or single cardiovascular diseases and risk factors (CVDRFs).
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References
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Journal ArticleDOI
2013 ACCF/AHA Guideline for the Management of Heart Failure: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
Clyde W. Yancy,Mariell Jessup,Biykem Bozkurt,Javed Butler,Donald E. Casey,Mark H. Drazner,Gregg C. Fonarow,Stephen A. Geraci,Tamara B. Horwich,James L. Januzzi,Maryl R. Johnson,Edward K. Kasper,Wayne C. Levy,Frederick A. Masoudi,Patrick E. McBride,John J.V. McMurray,Judith E. Mitchell,Pamela N. Peterson,Barbara Riegel,Flora Sam,Lynne W. Stevenson,W.H. Wilson Tang,Emily J. Tsai,Bruce L. Wilkoff +23 more
TL;DR: In this article, Anderson et al. proposed a new FAHA Chair, Jeffrey L. Anderson, MD, FACC, FAHA, Chair-Elect, Alice K. Jacobs et al., this article and Biykem Bozkurt.
Journal ArticleDOI
High risk of thrombosis in patients with severe SARS-CoV-2 infection: a multicenter prospective cohort study.
Julie Helms,Charles Tacquard,François Severac,Ian Leonard-Lorant,Mickaël Ohana,Xavier Delabranche,Hamid Merdji,Raphaël Clere-Jehl,Malika Schenck,Florence Fagot Gandet,Samira Fafi-Kremer,Vincent Castelain,Francis Schneider,Lelia Grunebaum,Eduardo Anglés-Cano,Laurent Sattler,Paul-Michel Mertes,Ferhat Meziani +17 more
TL;DR: Despite anticoagulation, a high number of patients with ARDS secondary to COVID-19 developed life-threatening thrombotic complications, and higher antICOagulation targets than in usual critically ill patients should therefore probably be suggested.
Journal ArticleDOI
Body mass index and mortality in heart failure: a meta-analysis.
Antigone Oreopoulos,Raj Padwal,Kamyar Kalantar-Zadeh,Gregg C. Fonarow,Colleen M. Norris,Finlay A. McAlister +5 more
TL;DR: Overweight and obesity were associated with lower all-cause and cardiovascular mortality rates in patients with CHF and were not associated with increased mortality in any study.
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Thromboembolism risk of COVID-19 is high and associated with a higher risk of mortality: A systematic review and meta-analysis.
Mahmoud B. Malas,Isaac Naazie,Nadin Elsayed,Asma Mathlouthi,Rebecca A. Marmor,Bryan M. Clary +5 more
TL;DR: Robust evidence from ongoing clinical trials is needed to determine the impact of thromboprophylaxis on TE and mortality risk of COVID-19.
Journal ArticleDOI
Prognostic Impact of Prior Heart Failure in Patients Hospitalized With COVID-19.
Jesús Álvarez-García,Samuel J. Lee,Arjun Gupta,Matthew Cagliostro,Aditya A. Joshi,Mercedes Rivas-Lasarte,Johanna Contreras,Sumeet S. Mitter,Gina LaRocca,Pilar Tlachi,Danielle L. Brunjes,Benjamin S. Glicksberg,Matthew A. Levin,Girish N. Nadkarni,Zahi A. Fayad,Valentin Fuster,Donna M. Mancini,Anuradha Lala +17 more
TL;DR: A retrospective analysis of 6,439 patients admitted for COVID-19 at 1 of 5 Mount Sinai Health System hospitals in New York City between February 27 and June 26, 2020 found history of HF was associated with higher risk of mechanical ventilation and mortality among patients hospitalized for CO VID-19, regardless of LVEF.