scispace - formally typeset
Journal ArticleDOI

Viper venom-induced inflammation and inhibition of free radical formation by pure compound (2-hydroxy-4-methoxy benzoic acid) isolated and purified from anantamul (Hemidesmus indicus R.Br) root extract

M.I. Alam, +1 more
- 01 Jan 1998 - 
- Vol. 36, Iss: 1, pp 207-215
Reads0
Chats0
TLDR
The present investigation explored the possible venom neutralizing effect of a pure compound isolated and purified from the methanolic root extract of Hemidesmus indicus R.Rr.
About
This article is published in Toxicon.The article was published on 1998-01-01. It has received 112 citations till now. The article focuses on the topics: Hemidesmus indicus.

read more

Citations
More filters
Journal ArticleDOI

Effects of Echis pyramidum snake venom on hepatic and renal antioxidant enzymes and lipid peroxidation in rats.

TL;DR: The acute phase oxidative stress due to an EPV injection points toward the importance of an early antioxidant therapy for the management of snake bites.
Journal ArticleDOI

Effect of 2‐hydroxy 4‐methoxy benzoic acid on an experimental model of hyperlipidaemia, induced by chronic ethanol treatment

TL;DR: Administration of 2‐hydroxy 4‐methoxy benzoic acid, the active principle of Hemidesmus indicus, an indigenous Ayurvedic medicinal plant in India, decreased lipids and lipoprotein concentrations significantly in an animal model of ethanol‐induced hyperlipidaemia.
Journal ArticleDOI

Glycosides derived from Hemidesmus indicus R. Br. root inhibit adherence of Salmonella typhimurium to host cells: receptor mimicry.

TL;DR: The results show the decreased ability of adherence of GHI‐treated S. typhimurium was due to a loss of surface hydrophobicity, which suggests that the biologically significant sugars present in GHI might be mimicking host cell receptor saccharides and thereby blocking the bacterial ligands from binding to the host cells.
Journal Article

Anti-snake venom activity of different extracts of Pouzolzia indica against Russel viper venom

TL;DR: The alcoholic and aqueous extracts of P. indica showed potent snake venom neutralizing capacity against Russell viper venom, and vegetable extracts with a range of antiophidian activities constitute an excellent alternative.
References
More filters
Journal ArticleDOI

Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels☆

TL;DR: The staining procedure for localizing superoxide dismutase on polyacrylamide electrophoretograms has been applied to extracts obtained from a variety of sources and could thus be assayed either in crude extracts or in purified protein fractions.
Journal ArticleDOI

Flavonoids, a class of natural products of high pharmacological potency

TL;DR: The few existing reports on the careful pharmacodynamic, pharmacokinetic and clinical studies which have been made have been summarized to provide a basis for a full-scale investigation of the therapeutic potential of flavonoids.
Journal ArticleDOI

Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.

R J Flower, +1 more
- 29 Mar 1979 - 
TL;DR: It is shown that similar events occur in the guinea pig perfused lung before inhibition by steroids of phospholipase A2 activity (and thus TXA2 generation), and a steroid-induced factor is discovered which mimics the anti-phospholipases effects of these anti-inflammatory agents.
Related Papers (5)