Journal ArticleDOI
Viper venom-induced inflammation and inhibition of free radical formation by pure compound (2-hydroxy-4-methoxy benzoic acid) isolated and purified from anantamul (Hemidesmus indicus R.Br) root extract
M.I. Alam,Aparna Gomes +1 more
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TLDR
The present investigation explored the possible venom neutralizing effect of a pure compound isolated and purified from the methanolic root extract of Hemidesmus indicus R.Rr.About:
This article is published in Toxicon.The article was published on 1998-01-01. It has received 112 citations till now. The article focuses on the topics: Hemidesmus indicus.read more
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Indian Sarsaparilla (Hemidesmus indicus): Recent progress in research on ethnobotany, phytochemistry and pharmacology
TL;DR: This review presents an exhaustive and updated review on the traditional, pharmacological and phytochemical aspects of H. indicus with notes on its quality control and toxicological information and compiles a list of Ayurvedic formulations and commercial preparations where the plant has been used as an active ingredient.
Journal ArticleDOI
Time-course of lipid peroxidation in different organs of mice treated with Echis pyramidum snake venom.
TL;DR: The results of this study showed that a single injection ofEP venom caused a significant lipid peroxidation in all the organs studied, suggesting an important role of oxidative stress in the cytotoxicity of EP venom.
Journal ArticleDOI
Cardioprotective and Other Beneficial Effects of Some Indian Medicinal Plants
TL;DR: Among these, Terminalia arjuna possesses the highest antioxidant potential and inhibit whole plasma oxidation in rats besides showing significant intestinal absorption and may possibly be responsible for their known beneficial therapeutic effects including their use in cardioprotection.
Journal ArticleDOI
Modified Salicylanilide and 3-Phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-dione Derivatives as Novel Inhibitors of Osteoclast Differentiation and Bone Resorption
Chun Liang Chen,Chun Liang Chen,Fei Lan Liu,Chia Chung Lee,Chia Chung Lee,Tsung Chih Chen,Tsung Chih Chen,Ahmed Atef Ahmed Ali,Ahmed Atef Ahmed Ali,Huey-Kang Sytwu,Deh-Ming Chang,Hsu Shan Huang,Hsu Shan Huang +12 more
TL;DR: These modified salicylanilides and 3-phenyl-2H-benzo[e][1,3]oxazine-2,4(3H)-diones could be potential lead compounds for the development of a new class of antiresorptive agents.
Journal ArticleDOI
Radiation protection of DNA and membrane in vitro by extract of Hemidesmus indicus.
TL;DR: Hemidesmus indicus root extract was found to protect microsomal membranes as evident from reduction in lipid peroxidation values and could also protect DNA from radiation induced strand breaks.
References
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Superoxide dismutase: Improved assays and an assay applicable to acrylamide gels☆
TL;DR: The staining procedure for localizing superoxide dismutase on polyacrylamide electrophoretograms has been applied to extracts obtained from a variety of sources and could thus be assayed either in crude extracts or in purified protein fractions.
Journal ArticleDOI
A colorimetric method for the determination of serum glutamic oxalacetic and glutamic pyruvic transaminases.
Stanley Reitman,Sam Frankel +1 more
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Flavonoids, a class of natural products of high pharmacological potency
TL;DR: The few existing reports on the careful pharmacodynamic, pharmacokinetic and clinical studies which have been made have been summarized to provide a basis for a full-scale investigation of the therapeutic potential of flavonoids.
Journal ArticleDOI
Anti-inflammatory steroids induce biosynthesis of a phospholipase A2 inhibitor which prevents prostaglandin generation.
R J Flower,G J Blackwell +1 more
TL;DR: It is shown that similar events occur in the guinea pig perfused lung before inhibition by steroids of phospholipase A2 activity (and thus TXA2 generation), and a steroid-induced factor is discovered which mimics the anti-phospholipases effects of these anti-inflammatory agents.
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M.I. Alam,Aparna Gomes +1 more
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