Proceedings ArticleDOI
Viscoelastic tissue mimicking phantom validation study with shear wave elasticity imaging and viscoelastic spectroscopy
Carolina Amador,Randall R. Kinnick,Matthew W. Urban,Mostafa Fatemi,James F. Greenleaf +4 more
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TLDR
In this study a VE tissue mimicking phantom was developed and its concentration was modified to vary the shear viscosity, and three VE phantoms were studied with SWE and hyper frequency viscoelastic spectroscopy.Abstract:
Acoustic radiation force-based shear wave elasticity (SWE) methods are used to characterize soft tissue pathologies by quantifying tissue viscoelastic (VE) properties. To adequately evaluate SWE methods measurements of VE properties, it is important to characterize VE properties of tissue mimicking phantoms with an independent method. In this study a VE tissue mimicking phantom was developed and its concentration was modified to vary the shear viscosity. Three VE phantoms were studied with SWE and hyper frequency viscoelastic spectroscopy (HFVS). The VE properties were quantified by fitting a Kelvin-Voigt fractional derivative model to the measured shear wave speed. The mean shear elasticity of the three phantoms was from 3.4 to 3.7 kPa, the mean shear viscosity was from 1.7 to 17.4 Pa•s and the power of the fractional derivative model varied from 0.6 to 0.9.read more
Citations
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Journal ArticleDOI
Why Are Viscosity and Nonlinearity Bound to Make an Impact in Clinical Elastographic Diagnosis
TL;DR: Evidence of the diagnostic capability of elastic parameters beyond linear stiffness is gaining momentum as a result of the technological and imaging developments in the field of biomechanics.
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Performance Study of a Torsional Wave Sensor and Cervical Tissue Characterization.
Antonio Callejas,Antonio Gomez,Juan Melchor,Miguel Riveiro,Paloma Massó,Jorge Torres,Modesto T. López-López,Guillermo Rus +7 more
TL;DR: The proposed methodology permits the reconstruction of the mechanical constants from the propagated shear wave, providing a proof of principle and warranting further studies to confirm the validity of the results.
Journal ArticleDOI
Local Phase Velocity Based Imaging of Viscoelastic Phantoms and Tissues
Piotr Kijanka,Matthew W. Urban +1 more
TL;DR: The ability of the proposed LPVI method to generate shear wave phase velocity maps at various frequencies in viscoelastic materials is shown, and a nonlinear least-squares problem is solved in order to locally estimate elasticity and viscosity parameters.
Journal ArticleDOI
Automated Compression Device for Viscoelasticity Imaging
Alireza Nabavizadeh,Randall R. Kinnick,Mahdi Bayat,Carolina Amador,Matthew W. Urban,Azra Alizad,Mostafa Fatemi +6 more
TL;DR: The design of an automated compression device that can be used to apply a ramp-and-hold force excitation for a predetermined duration of time and it houses an ultrasound probe for monitoring the creep response of the underlying tissue is presented.
Journal ArticleDOI
Acoustic Radiation Force-Induced Creep–Recovery (ARFICR): A Noninvasive Method to Characterize Tissue Viscoelasticity
TL;DR: Finite-element method simulations and experiments in tissue mimicking phantoms are used to validate and characterize the extent of viscoelastic quantification of ARFICR, and the results suggest that ARFicR can measure tissue vis coelasticity reliably.
References
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Book
Biomechanics: Mechanical Properties of Living Tissues
Yuan-Cheng Fung,Richard Skalak +1 more
TL;DR: This chapter discusses the mechanics of Erythrocytes, Leukocytes, and Other Cells, and their role in Bone and Cartilage, and the properties of Bioviscoelastic Fluids, which are a by-product of these cells.
Journal ArticleDOI
Biomechanics: Mechanical Properties of Living Tissues
Yuan-Cheng Fung,Richard Skalak +1 more
TL;DR: In this article, the authors present a sketch of the history and scope of the field of bio-physiology and discuss the meaning of the Constitutive Equation and the flow properties of blood.
Journal ArticleDOI
Magnetic resonance elastography by direct visualization of propagating acoustic strain waves
Raja Muthupillai,D. J. Lomas,Phillip J. Rossman,James F. Greenleaf,Armando Manduca,Richard L. Ehman +5 more
TL;DR: The results indicate that displacement patterns corresponding to cyclic displacements smaller than 200 nanometers can be measured and suggest the feasibility of a medical imaging technique for delineating elasticity and other mechanical properties of tissue.
Journal ArticleDOI
Shear wave elasticity imaging: a new ultrasonic technology of medical diagnostics
TL;DR: A physical and mathematical basis of SWEI is presented and some experimental results of pilot studies proving feasibility of this new ultrasonic technology are presented, including a theoretical model of shear oscillations in soft biological tissue remotely induced by the radiation force of focused ultrasound.
Journal ArticleDOI
Quantitative assessment of breast lesion viscoelasticity: initial clinical results using supersonic shear imaging.
Mickael Tanter,Jeremy Bercoff,A. Athanasiou,Thomas Deffieux,Jean-Luc Gennisson,Gabriel Montaldo,Marie Muller,Anne Tardivon,Mathias Fink +8 more
TL;DR: Preliminary clinical results directly demonstrate the clinical feasibility of this new elastography technique in providing quantitative assessment of relative stiffness of breast tissues and give valuable information that is complementary to the B-mode morphologic information.