Westernized diets lower arsenic gastrointestinal bioaccessibility but increase microbial arsenic speciation changes in the colon.
Citations
231 citations
Cites background from "Westernized diets lower arsenic gas..."
...Although bioavailability testing has focused primarily on soils, more research is also warranted for bioavailability assessment of other exposure media such as dust and foods (Alava et al. 2015; Juhasz et al. 2006; Menka et al. 2014)....
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178 citations
Cites background from "Westernized diets lower arsenic gas..."
...Rice may also contain minor amounts of organic As such as DMA (V) [28, 29]....
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...The iAs in rice is probably present both as As (III) and As (V) [27, 28]....
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...One recent in vitro study found that dietary composition might have an impact on the presystematic arsenical metabolism; a Westernized diet resulted in higher formation of MA (III) and monomethylmonothio arsonate (MMMTA (V)) than an Asian diet after 48 h incubation of these diets with rice in human colon suspensions [28]....
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...[28] Alava P, Du Laing G, Tack F, De Ryck T, Van De Wiele T....
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118 citations
106 citations
Cites background from "Westernized diets lower arsenic gas..."
...The acidic pH in the stomach increases arsenic bio-accessibility in comparison to the intestine [127]....
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...Arsenic undergoes a series of biotransformation in the gastrointestinal tract, including oxidation, reduction, methylation, and thiolation [127]....
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...Inorganic arsenic species are more likely to bind to the thiol containing amino acid in the endosperm cells of rice seed [127]....
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101 citations
References
938 citations
"Westernized diets lower arsenic gas..." refers background in this paper
...Summarizing the above paragraphs; as rice being one of the major source of arsenic through food and diet components like lipids and fiber affecting the bioaccessibility of ingested arsenic species we aimed to study whether and how bioaccessibility of As is affected by diet composition and further how these diets effect the biotransformations of ingested As. Arsenic through rice is major problem in western countries like America (Trenary et al., 2012) and Eastern countries like Bangladesh, India and Taiwan (Meharg and Rahman, 2003, Chowdhury et al., 2000, Pal et al., 2009), and there is significant difference between diet compositions of these two regions; Asian diet (low in fat, protein and high in carbohydrate) and Western diet (high fat and protein) (Suhana et al., 1999 and Park et al., 2006)....
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...…through rice is major problem in western countries like America (Trenary et al., 2012) and Eastern countries like Bangladesh, India and Taiwan (Meharg and Rahman, 2003, Chowdhury et al., 2000, Pal et al., 2009), and there is significant difference between diet compositions of these two…...
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750 citations
"Westernized diets lower arsenic gas..." refers background in this paper
...cardiovascular, and neurological effects, have been attributed to As exposure (Chen et al., 1992)....
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...The major sources of exposure are from food and water. cardiovascular, and neurological effects, have been attributed to As exposure (Chen et al., 1992)....
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665 citations
"Westernized diets lower arsenic gas..." refers background in this paper
...In a scenario of dietary As exposure, rice has been demonstrated to be one of the major foodstuffs contributing to human As exposure (Williams et al., 2007) and also widely consumed (Raab et al....
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...In a scenario of dietary As exposure, rice has been demonstrated to be one of the major foodstuffs contributing to human As exposure (Williams et al., 2007) and also widely consumed (Raab et al., 2009)....
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501 citations
467 citations
"Westernized diets lower arsenic gas..." refers methods in this paper
...The IVG method was previously validated against in vivo data for As bioaccessibility (Rodriguez and Basta, 1999) in the upper digestive tract (gastric, small intestine), whereas the SHIME has been validated against in vivo data for the colon microbial community composition and metabolic activity toward drugs and phytoestrogens (Molly et al....
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...The IVG method was previously validated against in vivo data for As bioaccessibility (Rodriguez and Basta, 1999) in the upper digestive tract (gastric, small intestine), whereas the SHIME has been validated against in vivo data for the colon microbial community composition and metabolic activity…...
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