Figure 3. Significant interactions between WMH loads per tract and cohort, impacting regional GM volumes in MCI, and AD, FTD, and PD patients (Eq. 3). The connections show the significant regions for each tract (FDR corrected pvalue<0.05). Colors indicate t-statistics, with colder colors indicating higher levels of atrophy (lower DBM values) relating to higher WMH burden. WMH=White Matter Hyperintensities. DBM= Deformation Based Morphometry. PD= Parkinson’s Disease. FTD= Fronto-temporal Dementia. MCI= Mild Cognitive Impairment. AD= Alzheimer’s Dementia.
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