Figure 4. Significant interactions between cohort and WMH loads per tract affecting cognitive scores in PD, FTD, MCI, and AD patients (FDR corrected p-value<0.05). Colors indicate the t-statistic values from the mixed effects models (eq. 4), with colder colors indicating poorer cognitive performance relating to higher WMH burden. WMH=White Matter Hyperintensities. PD= Parkinson’s Disease. FTD= Fronto-temporal Dementia. MCI= Mild Cognitive Impairment. AD= Alzheimer’s Dementia. All images in neurological format.
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