WHO Coronavirus Disease (COVID-19) Dashboard
01 Jan 2020-
TL;DR: Globally, as of 10,47am CEST, 28 May 2020, there have been 5,556,679 confirmed cases of COVID-19, including 351,866 deaths, reported to WHO.
Abstract: Globally, as of 10:47am CEST, 28 May 2020, there have been 5,556,679 confirmed cases of COVID-19, including 351,866 deaths, reported to WHO
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Merryn Voysey1, Clemens Sac.1, Shabir A. Madhi, Lily Yin Weckx2, P M Folegatti1, Parvinder K. Aley1, Brian Angus1, Vicky L. Baillie3, Shaun Barnabas4, Q E Bhorat, S Bibi1, Carmen Briner3, P Cicconi1, Andrea M. Collins5, R Colin-Jones1, Clare L. Cutland3, Thomas C. Darton6, Keertan Dheda7, Duncan Cja.8, Emary Krw.1, Katie J. Ewer1, Lee Fairlie3, Saul N. Faust9, Shuo Feng1, Daniela M. Ferreira5, Adam Finn10, Anna Goodman11, Catherine M. Green1, Christopher A Green12, Paul T. Heath13, Christopher Hill3, Helen Hill5, Ian Hirsch14, Hodgson Shc.1, Allen Izu, S Jackson1, D Jenkin1, Joe Ccd.1, S Kerridge1, Anthonet Koen, Gaurav Kwatra3, Rajeka Lazarus15, Alison M. Lawrie1, A Lelliott1, Vincenzo Libri16, Patrick J. Lillie17, R Mallory14, Mendes Ava.18, Eveline Pipolo Milan19, Angela M. Minassian1, Alastair McGregor20, Hazel Morrison1, Y Mujadidi1, Amit J Nana3, P J O’Reilly1, S D Padayachee, A Pittella, E Plested1, Katrina M Pollock, M N Ramasamy1, S Rhead1, Alexandre Vargas Schwarzbold21, Nisha Singh1, Andrew Smith22, R Song23, Matthew D. Snape1, Eduardo Sprinz24, Rebecca K. Sutherland25, R Tarrant1, E. Thomson26, M E Török27, Mark Toshner28, Turner Dpj.29, Johan Vekemans14, Tonya Villafana14, Watson Mee.1, C J Williams30, Alexander D. Douglas1, Hill Avs.1, Teresa Lambe1, Sarah C. Gilbert1, Andrew J. Pollard1 •
University of Oxford1, Federal University of São Paulo2, University of the Witwatersrand3, Stellenbosch University4, Liverpool School of Tropical Medicine5, University of Sheffield6, University of London7, Newcastle upon Tyne Hospitals NHS Foundation Trust8, University Hospital Southampton NHS Foundation Trust9, University Hospitals Bristol NHS Foundation Trust10, Guy's and St Thomas' NHS Foundation Trust11, University Hospitals Birmingham NHS Foundation Trust12, St George's, University of London13, AstraZeneca14, North Bristol NHS Trust15, University College Hospital16, University of Hull17, Escola Bahiana de Medicina e Saúde Pública18, Federal University of Rio Grande do Norte19, Northwest University (China)20, Universidade Federal de Santa Maria21, Glasgow Dental Hospital and School22, Boston Children's Hospital23, Universidade Federal do Rio Grande do Sul24, Western General Hospital25, University of Glasgow26, Cambridge University Hospitals NHS Foundation Trust27, University of Cambridge28, Nottingham University Hospitals NHS Trust29, Aneurin Bevan University Health Board30
TL;DR: ChAdOx1 nCoV-19 has an acceptable safety profile and has been found to be efficacious against symptomatic COVID-19 in this interim analysis of ongoing clinical trials.
3,741 citations
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TL;DR: The immunological principles that need to be taken into consideration in the development of COVID-19 vaccine strategies are discussed and their strengths and potential shortfalls are examined, and inferences about their chances of success are made.
Abstract: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the most formidable challenge to humanity in a century. It is widely believed that prepandemic normalcy will never return until a safe and effective vaccine strategy becomes available and a global vaccination programme is implemented successfully. Here, we discuss the immunological principles that need to be taken into consideration in the development of COVID-19 vaccine strategies. On the basis of these principles, we examine the current COVID-19 vaccine candidates, their strengths and potential shortfalls, and make inferences about their chances of success. Finally, we discuss the scientific and practical challenges that will be faced in the process of developing a successful vaccine and the ways in which COVID-19 vaccine strategies may evolve over the next few years.
761 citations
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Jobie Budd1, Jobie Budd2, Benjamin S. Miller1, Erin M. Manning1, Vasileios Lampos2, Mengdie Zhuang2, Michael Edelstein3, Geraint Rees2, Vincent C. Emery4, Molly M. Stevens5, Neil Keegan6, Michael J. Short2, Deenan Pillay2, Ed Manley7, Ingemar J. Cox2, Ingemar J. Cox8, David L Heymann9, Anne M Johnson2, Rachel A. McKendry1, Rachel A. McKendry2 •
TL;DR: The future of public health is likely to become increasingly digital, and the need for the alignment of international strategies for the regulation, evaluation and use of digital technologies to strengthen pandemic management, and future preparedness for COVID-19 and other infectious diseases is reviewed.
Abstract: Digital technologies are being harnessed to support the public-health response to COVID-19 worldwide, including population surveillance, case identification, contact tracing and evaluation of interventions on the basis of mobility data and communication with the public. These rapid responses leverage billions of mobile phones, large online datasets, connected devices, relatively low-cost computing resources and advances in machine learning and natural language processing. This Review aims to capture the breadth of digital innovations for the public-health response to COVID-19 worldwide and their limitations, and barriers to their implementation, including legal, ethical and privacy barriers, as well as organizational and workforce barriers. The future of public health is likely to become increasingly digital, and we review the need for the alignment of international strategies for the regulation, evaluation and use of digital technologies to strengthen pandemic management, and future preparedness for COVID-19 and other infectious diseases.
636 citations
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TL;DR: A meta-analysis to assess the prevalence of depression, anxiety, distress, and insomnia during the COVID-19 pandemic found that the general population and non-medical staff had a lower risk of distress than other populations, and Physicians, nurses, and non -medical staff showed a higher prevalence of insomnia.
628 citations
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Lixue Huang1, Qun Yao2, Xiaoying Gu3, Qiongya Wang2, Lili Ren2, Yeming Wang1, Yeming Wang3, Ping Hu2, Li Guo2, Min Liu3, Jiuyang Xu4, Xueyang Zhang4, Yali Qu2, Yanqing Fan2, Xia Li2, Caihong Li2, Ting Yu2, Jiaan Xia2, Ming Wei2, Li Chen2, Yanping Li2, Fan Xiao2, Dan Liu2, Jianwei Wang2, Xianguang Wang2, Bin Cao4, Bin Cao3, Bin Cao2 •
TL;DR: Wang et al. as discussed by the authors conducted an ambidirectional cohort study of COVID-19 survivors who had been discharged from Jin Yin-tan Hospital (Wuhan, China) between Jan 7 and May 29, 2020.
578 citations
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