Whole-genome haplotype reconstruction using proximity-ligation and shotgun sequencing.
Citations
4,806 citations
Cites methods from "Whole-genome haplotype reconstructi..."
...Ultimately, because Hi-C provides megabase-scale linkage information, the integration of this technology withCanu assembly graphs could lead to complete de novo assemblies that span entire mammalian chromosomes from telomere to telomere, as was recently demonstrated for the domestic goat genome (Bickhart et al. 2016)....
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...Alternatively, secondary information from technologies like 10x Genomics (Zheng et al. 2016) or Hi-C (Selvaraj et al. 2013) could be used to guide walks through the Canu graph....
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1,444 citations
1,393 citations
954 citations
Cites methods from "Whole-genome haplotype reconstructi..."
...This limitation can be circumvented by several methods, including sequencing parents, sequencing proximity ligated fragments (Selvaraj et al., 2013), or dilution and barcoding strategies during template preparation to allow long read assembly (Kuleshov et al., 2014; Voskoboynik et al., 2013)....
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...This limitation can be circumvented by several methods, including sequencing parents, sequencing proximity ligated fragments (Selvaraj et al., 2013), or dilution and barcoding strategies during template preparation to allow long read assembly (Kuleshov...
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886 citations
References
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