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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2163-2196
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TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
About: 
This article is published in The Lancet.The article was published on 2012-12-15 and is currently open access. It has received 7021 citations till now. The article focuses on the topics: Years of potential life lost & Global health.

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Disc cell senescence in intervertebral disc degeneration: Causes and molecular pathways

Chencheng Feng, +5 more
- 18 May 2016 - 
TL;DR: It was found that, during the process of IDD, age-related damages together with degenerative external stimuli activated both p53-p21-Rb and p16-RB pathways to induce disc cell senescence, and disc cellsenescence was regulated by multiple signaling pathways, suggesting the complex regulating network of disc cell Senescence.
Journal ArticleDOI

Genetic predisposition to schizophrenia associated with increased use of cannabis

Robert Power, +9 more
- 01 Nov 2014 - 
TL;DR: In a sample of 2082 healthy individuals, an association is shown between an individual’s burden of schizophrenia risk alleles and use of cannabis, suggesting that part of the association between schizophrenia and cannabis is due to a shared genetic aetiology.
Journal ArticleDOI

Systematic review and assessment of validated case definitions for depression in administrative data

Kirsten M. Fiest, +9 more
- 17 Oct 2014 - 
TL;DR: This study systematically review the literature on validated case definitions to identify depression using International Classification of Disease and Related Health Problems (ICD) codes in administrative data and develops an enhanced case definition to identify persons with depression in ICD-coded hospital data.
Journal ArticleDOI

Nonpharmacologic Versus Pharmacologic Treatment of Adult Patients With Major Depressive Disorder: A Clinical Practice Guideline From the American College of Physicians

Amir Qaseem, +2 more
- 01 Mar 2016 - 
TL;DR: This guideline is to summarize and grade the evidence on the comparative effectiveness and safety of nonpharmacologic treatments and SGAs (including serotonin reuptake inhibitors, serotonin norepinephrine reuptakes inhibitors, bupropion, mirtazapine, nefazodone, and trazodone), alone or in combination, for MDD.
Journal ArticleDOI

The Epidemiology of Cardiovascular Diseases in Sub-Saharan Africa: The Global Burden of Diseases, Injuries and Risk Factors 2010 Study

Andrew E. Moran, +5 more
- 01 Nov 2013 - 
TL;DR: The leading CVD cause of death and disability in 2010 in sub-Saharan Africa was stroke; the largest relative increases in CVD burden between 1990 and 2010 were in atrial fibrillation and peripheral arterial disease.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Book

Cancer Incidence in Five Continents

Freddie Bray, +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
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The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

Ronald C. Kessler, +8 more
- 18 Jun 2003 - 
TL;DR: Notably, major depressive disorder is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment, and while the recent increase in treatment is encouraging, inadequate treatment is a serious concern.
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

Christopher J L Murray, +1 more
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
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Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

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