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Years lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990-2010: a systematic analysis for the Global Burden of Disease Study 2010

Theo Vos, +363 more
- 15 Dec 2012 - 
- Vol. 380, Iss: 9859, pp 2163-2196
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TLDR
Prevalence and severity of health loss were weakly correlated and age-specific prevalence of YLDs increased with age in all regions and has decreased slightly from 1990 to 2010, but population growth and ageing have increased YLD numbers and crude rates over the past two decades.
About: 
This article is published in The Lancet.The article was published on 2012-12-15 and is currently open access. It has received 7021 citations till now. The article focuses on the topics: Years of potential life lost & Global health.

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Topical analgesics for acute and chronic pain in adults ‐ an overview of Cochrane Reviews

Sheena Derry, +7 more
- 12 May 2017 - 
TL;DR: Thirteen Cochrane Reviews assessed the efficacy and harms from a range of topical analgesics applied to intact skin in a number of acute and chronic painful conditions.
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Tramadol for neuropathic pain in adults

Rudolf Duehmke, +5 more
- 15 Jun 2017 - 
TL;DR: To assess the analgesic efficacy of tramadol compared with placebo or other active interventions for chronic neuropathic pain in adults, and the adverse events associated with its use in clinical trials, six randomised, double-blind studies are identified.
Journal ArticleDOI

Osteoarthritis research priorities : a report from a EULAR ad hoc expert committee

Philip G. Conaghan, +3 more
- 13 Mar 2014 - 
TL;DR: An ad hoc committee of OA researchers, clinicians and patients created to consider a research agenda focussed on the areas of epidemiology, pathogenesis, imaging and biomarkers, and therapies has deliberated and listed research needs in these areas.
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Cervico‐thoracic or lumbar sympathectomy for neuropathic pain and complex regional pain syndrome

Sebastian Straube, +3 more
- 02 Sep 2013 - 
TL;DR: The practice of surgical and chemical sympathectomy for neuropathic pain and CRPS is based on very little high quality evidence and should be used cautiously in clinical practice, in carefully selected patients, and probably only after failure of other treatment options.
Journal ArticleDOI

A small molecule promotes cartilage extracellular matrix generation and inhibits osteoarthritis development.

Yuanyuan Shi, +16 more
- 23 Apr 2019 - 
TL;DR: It is shown that BNTA, a small molecule identified in a chemical screen, promotes ECM generation in human osteoarthritic chondrocytes and cartilage explants, and suppresses pathology in a rat model of osteOarthritis.
References
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Journal ArticleDOI

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

Rafael Lozano, +195 more
- 15 Dec 2012 - 
TL;DR: The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 aimed to estimate annual deaths for the world and 21 regions between 1980 and 2010 for 235 causes, with uncertainty intervals (UIs), separately by age and sex, using the Cause of Death Ensemble model.

The Global Burden of Disease Study

Christopher J L Murray, +1 more
Book

Cancer Incidence in Five Continents

Freddie Bray, +11 more
TL;DR: The aim of this study was to establish a database of histological groups and to provide a level of consistency and quality of data that could be applied in the design of future registries.
Journal ArticleDOI

The epidemiology of major depressive disorder: results from the National Comorbidity Survey Replication (NCS-R).

Ronald C. Kessler, +8 more
- 18 Jun 2003 - 
TL;DR: Notably, major depressive disorder is a common disorder, widely distributed in the population, and usually associated with substantial symptom severity and role impairment, and while the recent increase in treatment is encouraging, inadequate treatment is a serious concern.
Book

The global burden of disease: a comprehensive assessment of mortality and disability from diseases injuries and risk factors in 1990 and projected to 2020.

Christopher J L Murray, +1 more
TL;DR: This is the first in a planned series of 10 volumes that will attempt to "summarize epidemiological knowledge about all major conditions and most risk factors" and use historical trends in main determinants to project mortality and disease burden forward to 2020.
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