Yeast Systems Biology: Towards a Systems Understanding of Regulation of Eukaryotic Networks in Complex Diseases and Biotechnology
Cites background from "Yeast Systems Biology: Towards a Sy..."
...Next-generation molecular and high-throughput techniques are opening new avenues of research towards the discovery of mechanisms and networks underlying complex multifactorial diseases (14-19)....
...From here, further comprehensive systems-level analyses, with SB multi-omics methods (experimental and computational) are needed (14-16)....
...Understanding these systems and networks in their functional and dysfunctional states can reveal characteristic molecular signatures and candidates for tailored interventions, according to the precision medicine paradigm (14-17, 19, 27-29)....
...From here, further comprehensive systemslevel analyses, with SB multi-omics networks methods, both experimental and computational, are needed (point 2) (14-16)....
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The basic characteristics of the yeast Saccharomyces cerevisiae , with main molecular mechanisms, biological networks and subcellular organization essentially conserved in all eukaryotes, make it an optimum model eukaryote for systems biology studies.