Are all vaccines RNA?
Answers from top 8 papers
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| Papers (8) | Insight |
|---|---|
394 Citations | Naked, non-infectious, self-replicating RNA may be an excellent candidate for the development of new cancer vaccines. |
| As new cancer antigens come to the forefront with novel RNA encapsulation and targeting techniques, RNA vaccines may prove to be a vital, safe and robust method to initiate patient-specific anti-tumor efficacy. | |
| Also, unlike DNA‐based vaccines, there is little danger of incorporation of RNA sequences into the host genome. | |
| We also identified altered expression of these lncRNAs in RNA-sequencing (RNA-seq) data from a cohort of children following immunization with intranasal live attenuated influenza vaccine, suggesting a common role across several diverse vaccines. | |
15 Citations | Therefore, RNA adjuvants have broad applicability and can be used with all conventional vaccines to improve vaccine efficacy qualitatively and quantitively. |
| From this we conclude that sa-RNA is a promising platform for vaccines against viral diseases. | |
147 Citations | Our findings imply that bioavailability of recombinant RNA vaccines in vivo highly depends on the density and the maturation stage of DCs at the administration site and are of importance for the design of RNA-based clinical immunotherapy protocols. |
15 Citations | This suggests that protein-based vaccines formulated using RNA adjuvant function as live-attenuated vaccines. |