Are there biomarkers that can predict vitiligo treatment response?
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Biomarkers that can predict vitiligo treatment response have been identified in the studies conducted by Yang et al. , El-Domyati et al. , and Howell et al. . Yang et al. found that short disease duration and upregulation of immune active genes, such as CXCL10, FCRL3, and TCR, were associated with a favorable response to immune suppressive therapy. El-Domyati et al. demonstrated that elevated CXCL10 levels in lesional skin correlated with increased leukocytic infiltrate and treatment response. Howell et al. provided biomarkers associated with responsiveness to JAK inhibitors. These findings suggest that clinical parameters and gene expression biomarkers, such as CXCL10, FCRL3, and TCR, can be used to predict vitiligo treatment response.
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| Papers (5) | Insight |
|---|---|
5 Citations | Yes, the paper suggests that serum chemokines, specifically CXCL9 and CXCL10, may serve as potential biomarkers for predicting treatment response in vitiligo patients. |
Patent 17 Jan 2018 1 Citations | The provided paper does not mention any biomarkers that can predict vitiligo treatment response. The paper is about a biomarker for diagnosing vitiligo susceptibility and predicting its occurrence, not treatment response. |
| Yes, the paper provides biomarkers that are associated with or predictive of a subject's responsiveness to a JAK inhibitor for vitiligo treatment. | |
3 Citations | No, there are currently no biomarkers shown to predict treatment response to vitiligo therapy. |
| Yes, the paper suggests that systemic CXCL10 can be used as a biomarker to predict vitiligo treatment response. |
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