Can apoptosis be prevented?
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62 Citations | Thus, when this conflict was prevented by serum depletion, apoptosis was suppressed. |
The presence of apoptotic cells was prevented completely by benzyloxycarbonyl‐Val‐Ala‐fluoromethyl ketone (a nonspecific caspase inhibitor), indicating that apoptosis was mediated by caspase activation. | |
47 Citations | Apoptosis can be blocked by caspase inhibitors. |
Apoptosis could be accelerated or prevented by modifying culture conditions or cell density, indicating that extracellular signals influenced the epimastigote decision between life and death. | |
196 Citations | Moreover, induction of apoptosis could be prevented by treating cells with an inhibitor of casp-8. |
12 Citations | However, apoptosis can be inhibited by adding protein synthesis inhibitors, indicating de novo protein synthesis may be partially responsible for apoptosis. |
108 Citations | As in many other cellular lineages susceptible to apoptosis, these degenerative changes can be prevented by treatment with the endonuclease antagonist, aurintricarboxylic acid, or by inhibiting de novo RNA or protein synthesis. |
29 Citations | Apoptosis can be prevented by inhibitors of transcription or translation, suggesting a need for macromolecular synthesis in the apoptotic process. |
45 Citations | Terminal apoptosis was thus prevented. |
Apoptosis and barrier dysfunction could be prevented by caspase inhibition. |
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