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Can B cells recognize viral infected cells? 

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We infer from these results that B cells could constitute a reservoir of infectious virus in infected patients.
We conclude that latently infected peripheral blood B cells display the molecular hallmarks of classical antigen-selected memory B cells.
We present evidence for the direct recognition of infected B cells by CD4 and CD8 T cells.
We conclude that the EBV-infected cells in vivo are B cells with a nonactivated phenotype.
The nature of B cell infection was distinct from innate immune cell infection in that mature B cells were infected noncytopathically in contrast to the lytic infection of macrophages and dendritic cells.
We conclude that viral HA can be used in conjunction with cell surface and intracytoplasmic stains in multicolor flow cytometry to provide detailed phenotypic and functional information on virus HA-specific B cells.
Long-term follow-up of this expanded B cell subset within the infected individuals will help determine whether these cells are predictors of more-serious clinical manifestations.
The failure of the immune system to eliminate these virus‐infected B cells in XLP is clearly not caused by a B‐cell‐specific defect.

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